UNIVERSITY OF PENNSYLVANIA

DEPARTMENT OF BIOENGINEERING

COMPUTATIONAL BIOLOGY RESEARCH GROUP

 
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Principal Investigator: Ravi Radhakrishnan, PhD.

 

 

University of Pennsylvania

 

School of Engineering and Applied Sciences

Assistant Professor of Bioengineering

Assistant Professor of Chemical & Biomolecular Engineering

Cheminformatics Core of the Penn Center of Molecular Discovery

 

School of Medicine

Assistant Professor of Biochemistry and Biophysics

Graduate Group Member Genomics & Computational Biology

Member of Institute for Targeted Medicine and Therapeutics

 

 

Mailing Address

University of Pennsylvania

Department of Bioengineering

240 Skirkanich Hall, 210 S. 33rd St.

Philadelphia, PA, 19104

 

Office: 540 Skirkanich Hall

Ph: 1 (215) 898 0487;

Fax: 1(215) 573 2071

Email: rradhak@seas.upenn.edu

 

Lab: 540 Skirkanich Hall

Ph: 1( 215) 898 0592

 

 

Education:

1995 B. Tech.   Indian Institute of Technology

2001 PhD          Cornell University

 

Postdoctoral Training:

2000-2002  Massachusetts Institute of Technology

2002-2004  New York University and the Courant Institute

2003           Howard Hughes Medical Institute

 

Honors:

1991-1995 CSIR Undergraduate Fellowship

1995-1996 Cornell University Graduate Fellowship

2003 Computational Associate of HHMI

2008 HP Young Investigator Award

 

 

Molecular Systems Biology through multiscale modeling and high-performance computing

 

Our research interests lie at the interface of chemical physics and molecular biology. Our goal is to provide atomic and molecular level characterization of complex biomolecular systems and formulate quantitatively accurate microscopic models for predicting the interactions of various therapeutic agents with innate biochemical signaling mechanisms.

 

We employ several computational algorithms ranging from techniques to treat electronic structure, molecular dynamics, Monte Carlo simulations, stochastic kinetic equations, and complex systems analyses in conjunction with the theoretical formalisms of statistical and quantum mechanics, and high performance computing in massively parallel architectures.

 

CURRENT RESEARCH PROJECTS

  • DNA Repair & Molecular Carcinogenesis
  • Cancer Therapeutics: Receptor-mediated signaling
  • Drug resistance in receptor tyrosine kinase inhibitors
  • Targeted drug delivery: Model-driven design of functional nanocarriers  
  • Signal transduction in biochemical networks  

 

 

Research Canvas: presentations and movies related to our research

Media Coverage

 

 

COURSES:

 

BE324: Physical Principles in Bioengineering

 

BE459/559: Multiscale Modeling of Biochemical Systems

 

 

 

COMPUTING RESOURCES

 

 

Dissemination: distribution of software developed

 

 

 

 

Undergraduate Research

 

Undergraduate Research for BE, CBE, PHYS, CHEM, BMB majors

Juniors and Seniors CONTACT US with your CV and a brief statement of interest

Copyright 2004 RADHAKRISHNAN RESEARCH GROUP. All Rights Reserved. CONTACT US