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Welcome to the Penn Center for Molecular Discovery!
The Penn Center for Molecular Discovery (PCMD), founded at the University of Pennsylvania, is a multi-disciplinary center that screens small molecules from around the world in search of new, potentially useful biologically effective agents. The Penn Center for Molecular Discovery is housed within the Institute for Medicine and Engineering.The Director of the Center is Scott Diamond, Ph.D., the Arthur E. Humphrey Professor of Chemical and Biomolecular Engineering. The PCMD contributes to a massive, public-domain database (PubChem) where interactions between the NIH repository and thousands of biological targets can be data-mined at an unprecedented level. |
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Click on the image above to view a Windows Media video of the robot arm in action. |
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Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L
Parag P. Shah, Michael C. Myers, Mary Pat Beavers, Jeremy E. Purvis, Huiyan Jing, Heather J. Grieser, Elizabeth R. Sharlow, Andrew D. Napper, Donna M. Huryn, Barry S. Cooperman, Amos B. Smith, III, and Scott L. Diamond
Mol Pharmacol 2008 74: 34-41. Published online April 10, 2008
[Abstract] [Full Text] [PDF] |
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Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain.
Mary Pat Beavers, Michael C. Myers, Parag P. Shah, Jeremy E. Purvis, Scott L. Diamond, Barry S. Cooperman, Donna M. Huryn, and Amos B. Smith.
J Chem Inf Model. 2008 48(7):
[Abstract] [Full Text] [PDF] |
Completed High-Throughput Screens (HTS)
Solicitation of Assays for High Throughput Screening (HTS) in the Molecular Libraries Probe Production Centers Network (MLPCN)
The new Program Announcements for the Solicitation of Assays for High Throughput Screening (HTS) in the Molecular Libraries Probe Production Centers Network (MLPCN) (X01) & (R03) have been released. Please follow the links below to each announcement.
About The Penn Center for Molecular Discovery (PCMD)
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