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Bioengineering Graduate
Group Faculty Members
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| Kristy Arbogast , Ph.D. |
Pediatric biomechanics towards the development of improved child anthropomorphic
dummies and the enhancement of the mechanistic understanding of unintentional injuries.
| Norman Badler, Ph.D. |
Director, Center for Human Modeling and Simulation
Computer graphics, human movement simulation and animation, kinematics and
dynamics, three-dimensional object representations, interactive software and systems
design, facial expression synthesis, artificial intelligence, process simulation and
reasoning, representation of functionality, semantics of motion verbs, dynamic visual
scene analysis,integrated graphics and language system.
| Vijay Balasubramanian, Ph.D. |
Merriam Term Assistant Professor of Physics More Info |
String theory - origin of cosmological constant; cosmology and physics of singularities;
black hole thermodynamics; information transmission in biological systems.
| Gordon Baltuch,M.D., Ph.D. |
Associate Professor of Neurosurgery
Director, Center for Functional and Restorative Neurosurgery
Novel surgical strategies for the treatment of epilepsy and degenerative diseases.
The biology of glia in disease.
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Associate Professor The Childrens Hospital of Philadelphia Division of Stress Neurobiology |
Identifying the cellular basis for individual vulnerability to stress, i.e., why are some
individuals more prone to stress-related diseases than others. Additionally, her
laboratory is investigating the effects of sex hormones on brain function and behavior.
| Dan Bogen, Ph.D. |
Professor of Bioengineering
Professor of Bioengineering in Medicine
Professor of Rehabilitation Medicine
Professor of Bioengineering in Pediatrics
107 Hayden Hall
(215) 573-2726
Cognitive rehabilitation; rehabilitation product design; toys for disabled children;
customized manufacturing, and adaptive technology for cognitive and physical
impairments.
| Dawn Bonnell, Ph.D. |
Materials Science & Engineering
Mechanical and electrical interface properties; local electronic structure of oxides
at chemical and structural defects; electronic structure variation occurring during
brittle fracture.
| David Brainard, Ph.D. |
Human vision, machine vision and computational modeling of visual processing.
| Charles R. Bridges, M.D., Sc.D. |
Associate Professor Surgery,
Division of Cardiothoracic Surgery
Investigation of candidate therapeutic
transgenes for heart failure and
coronary artery disease; novel strategies for adeno-associated
virus-mediated
transgene delivery including cardiopulmonary bypass with in-situ cardiac isolation;
experimental models of heart failure, including isolated-perfusedrodent heart models
with microsurgical heterotopic heart transplantation;cardiac mechanics: experimental
assessment of cardiac function and theoretical models of ventricular mechanics.
| Gershon Buchsbaum, Ph.D. |
Professor of Bioengineering
Deputy Chair, Bioengineering
Member, Institutes for Neurological Sciences
Member, Institute for Medicine and Engineering
Member, Institute for Research in Cognitive Science
240 Skirkanich Hall 107 Hayden Hall (215) 573-2726 |
Human visual perception in simple and spatially complex visual fields; visual signal
processing and image coding. Modeling of retinal visual system architecture and function.
| Jason Burdick, Ph.D. |
Wilf Family Term Assistant Professor of Bioengineering
102 Hayden Hall 215-898-8537 |
Polymeric Biomaterials Laboratory, Photopolymerization, Drug Delivery, Cartilage and
Bone Tissue Engineering, Spinal Cord Injury
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| Christopher S. Chen, M.D., Ph.D. |
Skirkanich Professor of Innovation in Bioengineering
| 510 Skirkanich Hall (215) 746-1754 |
Micro- and Nanotechnology; Transduction of mechanical forces by cells; Relationship
between cellular and multicellular structure and biological function; Angiogenesis; Cancer;
and Stem cell biology. Dr. Chen's laboratory studies how the interactions between cells
and their surrounding tissue microenvironment drives their behavior. His group develops
novel microfabriaction and nanotechnology-based tools to manipulate and monitor these
interactions in order to better understand how cells function in normal and disease contexts.
| Artur V. Cideciyan, Ph.D. |
Research Associate Professor
Scheie Eye Institute, University of Pennslyvania |
| Mortimer M. Civa, Ph.D. |
Department of Physiology
Phone: (215) 898-8773
My laboratory is primarily concerned with: (1) the mechanisms of movement of solutes and water across epithelial membranes, (2) the regulation of that movement, and (3) the clinical implications of altering the underlying mechanisms and regulation. Our current focus is on the mechanisms and regulation of aqueous humor inflow into, and exit from, the eye, and their implications for the treatment of glaucoma. Two broad lines of in vitro work are in progress using the techniques of patch clamping, molecular biology, fluorescence microscopy and electronic cell sorting. First, we are seeking to identify the molecular basis for chloride-channel activity, which likely limits the rate of ciliary epithelial secretion. Second, we are also testing our current hypothesis concerning the autocrine and paracrine basis for purinergic regulation of aqueous humor secretion and efflux. We are testing our hypotheses, developed on the basis of our in vitro work, using measurements of intraocular pressure in the mouse.
| Akiva Cohen, Ph.D. |
Assistant Professor of Pediatrics
Department of Neurology
Perception of spatial layout, perceptual calibration, and binocular vision.
| Yale Cohen, Ph.D. |
Associate Professor
Department of Otorhinolaryngology:Head and Neck Surgery
University of Pennsylvania School of Medicine
3400 Spruce - 5 Ravdin
Philadelphia, PA 19104
My research program examines how the brain creates internal representations of the external world. By generating models of neural activity (e.g., first-order models or whitening models that are inspired by natural-scene statistics) and through quantitative analyses, such as those inspired by information theory or classification and decoding algorithms, my laboratory takes a systems-level circuit approach to test how behaviorally-relevant information is coded, represented, and transformed along defined neural circuits. The long-term goal of this research is to understand how brain areas interact and how these interactions relate to sensation, perception, and action at the level of brain networks.
In our major line of research, we investigate vocalization processing from low-level feature extraction to the higher-order mechanisms involved in processing the "meaning" of vocalizations. In a second, smaller line of research, we investigate the role of salience and attention in adaptive, goal-directed spatial behavior. Finally, other research in the laboratory investigates auditory spatial and non-spatial information processing.
| Russell J. Composto, Ph.D. |
401 LRSM (215) 898-4451 |
Polymer surfaces and interfaces , wetting, adhesion, adsorption, polymer precursors
to ceramics, ion scattering.
| Diego Contreras, M.D., Ph.D. |
Associate Professor, Dept of Neuroscience
School of Medicine
Intracellular recordings with sharp electrodes and optical recordings with voltage sensitive
dyes in vivo and in vitro. Information encoding in the visual system.
| Douglas Coulter, Ph.D. |
Epilepsy, neuronal excitability, CNS rhythm generation, GABA receptors, development
of neurotransmitter receptors and ion channels, synaptic function
| John Crocker, Ph.D. |
Skirkanich Assistant Professor of Innovation in Chemical Engineering
Chemical and Biomolecular Engineering
Institute for Medicine and Engineering
Pennsylvania Muscle Institute
Cell mechanics and rheology, self-assembly by molecular recognition, soft glasses,
single-molecule science, colloidal interactions, optical trapping
| Christos Davatzikos, Ph.D. |
Director, Section of Biomedical Image Analysis
Professor, Department of Radiology
Image processing and analysis, Deformable models and registration, computational anatomy,
Neuroimaging of Alzheimer's Disease and schizophrenia, Modeling and analysis methods for
surgical planning and guidance, Genotype/Phenotype relationships examined via imaging methods.
| Peter F. Davies, Ph.D. |
Professor of Pathology and Laboratory Medicine
Professor of Bioengineering
IME - 1010 Vagelos Labs (215) 898-4647 |
Molecular mechanisms of cardiovascular diseases, particularly arterial biology and
pathology (atherosclerosis). Mechanisms of interaction of hemodynamic forces with
the vascular endothelium and vascular cell-cell interactions.Experimental approaches
ranging from cell and molecular biology, membrane biophysics, to biomechanics and
computational fluid dynamics.
| William F. DeGrado, Ph.D. |
Macromolecule structure and function, de novo design of proteins, design of small
molecules that inhibit cell interactions, membrane-active peptides.
| Jim Delikatny, Ph.D. |
Research Associate Professor of Radiology
MR spectroscopy, MR imaging, anticancer drugs, lipid metabolism, cancer pharmacology
| Scott Diamond, Ph.D. |
Arthur E. Humphrey Professor of Chemical Engineering Professor of Bioengineering Director, Penn Center for Molecular Discovery Associate Director, Institute for Medicine and Engineering |
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IME - 1010 Vagelos Labs (215) 898-8652 |
Endothelial cell mechano-biology, drug and gene delivery, thrombosis and thrombolysis,
biotransport phenomena.
| Professor of Chemical and Biomolecular Engineering Professor of Bioengineering Professor of Mechanical Engineering and Applied Mechanics Member: Institute for Medicine and Engineering |
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129 Towne (215) 898-4809 |
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Membrane & Cytoskeleton thermodynamics, mechanics, self-assembly, and adhesion/cohesion in disease and
differentiation, including the strong influence of microenvironment mechanics on tissue cell differentiation.
Self-assembling polymer macro-surfactants as synthetic viruses for drug delivery (eg. "Polymersomes") and as
'better materials for better biology". Cell systems of particular interest include myocytes, stem cells, and
blood cells. Single molecule biophysics and mechanochemistry, especially Atomic Force Microscopy
nano-methods. Statistical mechanics of self-assembly, self-organization, networks, proteins, and polymers,
with computational emphasis.
| Research Associate Professor Department of Radiology School of Medicine 356 Stemmler Hall 36th and Hamilton Walk Philadelphia, PA 191 |
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215-349-5274 |
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The Cardiovascular Research Group develops and applies novel MR imaging and analysis tools for the study of cardiovascular function and flow.
| Paul Ducheyne, Ph.D. |
Professor of Bioengineering
Professor of Orthopaedic Surgery Research
Director of Center for Bioactive Materials and Tissue Engineering
Member, Institute for Medicine and Engineering
115 Hayden Hall (215) 898-1521 |
Biomaterials and Tissue Engineering. In vitro synthesis of musculoskeletal tissues. Bioactive ceramics,
including hydroxyapatite, bioactive glass and bioactive composites. Porous metals: surface analysis,
biocompatibility and electrochemical properties. Materials engineering, mechanical properties, design
and stress analysis. Orthopaedic and dental applications. Implant retrieval and analysis.
| James Eberwine, Ph.D. |
Molecular basis of neuronal functioning; molecular and bioprocess fingerprints of various
cell types and disease states.
| David M. Eckmann, Ph.D., M.D. |
Member of The Institute for Medicine and Engineering
Pulmonary and cardiovascular biofluid mechanics and biotransport phenomena.
| Wafik S. El-Deiry, M.D., Ph.D. |
Associate Professor of Medicine
Associate Professor of Genetics
Associate Professor of Pharmacology
Assistant Investigator, Howard Hughes Medical Institute
Director, Laboratory of Molecular Oncology and Cell Cycle Regulation
215-898-9072
The EL-DEIRY LAB is a Molecular Oncology Laboratory dedicated to the identification
and characterization of cell cycle and cell death abnormalities in chemo- and radioresistant cancers.
| Dawn M. Elliott, Ph.D. |
Associate Professor of Bioengineering
Member, Institute for Medicine and Engineering
424 Stemmler (215) 898-5583 |
Biomechanics of collagenous soft tissues, intervertebral disc, tendon and ligament, meniscus
and articular cartilage biomechanics in health, aging, degeneration, and injury.
| Nader Engheta, Ph.D. |
Biologically inspired polarization-difference imaging, fractional calculus in electrodynamics,
wave interaction with complex media.
| Charles Epstein, Ph.D. |
Several Complex Variables, Deformations of Singularities, Microlocal Analysis and Index
Theory, Image Reconstruction.
| Kenneth R. Foster, Ph.D., P.E. |
Professor of Electrical Engineering
| 106 Hayden Hall | (215) 898-8534 |
Biomedical applications of nonionizing radiation from audio through microwave frequency ranges, including
hyperthermia and clinical impedance techniques, dielectric properties of tissues, biological molecules,
suspensions, transport properties of complex suspensions, environmental issues related to nonionizing radiation.
| James C. Gee, Ph.D. |
Aspects of computational anatomy and biomedical computing. Topics include: Image registration and segmentation;
Pattern analysis; Morphometry; Diffusion tensor image processing; Imaging studies of brain structure and function.
| Jerry Glickson, Ph.D. |
| Yale E. Goldman, M.D., Ph.D. |
Professor of Physiology
Member of The Institute for Medicine and Engineering
Molecular mechanism of muscle contraction and protein synthesis relating structural, mechanical
and biochemical events in the contractile proteins and ribosomal elongation factors.
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Cardiac Surgery Attending Surgeon Hospital of University of Pennsylvania |
Associate Professor of Surgery
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| Mark Goulian, Ph.D. |
Associate Professor of Biology and of Physics and Astronomy
Member, Institute for Medicine and Engineering,
Cell signalling; explore design principles underlying circuits used by cells to tranduce,
interpret, and respond to
their enviroment.
| M. Sean Grady, M.D. |
Memory dysfunction resulting from traumatic brain injury and minimally invasive neurosurgery
| Joel H. Greenberg, Ph.D. |
Cerebral blood flow and metabolism in various physiological conditions: stroke, ischemia,
functional activation, systemic hypertension; and Positron Emission Tomography.
| Murray Grossman, Ph.D. |
Department of Cognitive Neurology
University of Pennsylvania School of Medicine
| Daniel A. Hammer, Ph.D. |
Ennis Professor of Bioengineering
Professor of Chemical Engineering
Member: Institute for Medicine and Engineering
535 Skirkanich Hall (215) 573-6761 |
Cellular bioengineering, cell adhesion, virus - cell interactions, membrane dynamics and
structure, novel biomaterials and biomimetics.
| Meenhard Herlyn, Ph.D. |
Stem cells in tumor development, progression and therapy
| Kurt Hankensen. D.V.M., M.S., Ph.D. |
Assistant Professor of Cell Biology
Regulation of mesenchymal stem cell quiescence, proliferation, and fate; osteoblast-adipocyte
reciprocal differentiation; bone formation and regeneration; cell-extracellular matrix interactions
| Paul A. Janmey, Ph.D. |
Professor of Physiology
IME - 1010 Vagelos Labs
Defining PIP2 and other phosphoinositide-binding sites on proteins; cytoskeletal functions of MAP2 and tau;
interactions among different cytoskeletal filaments.
| Peter Lloyd Jones |
Director, Penn/CMREF Center for Pulmonary Arterial Hypertension Research
Our research focuses on the role of homeobox gene transcription factors and their targets in
lung development and disease, including pulmonary arterial hypertension and breast cancer
metastasis to the lung vasculature.
Assistant Professor Department of Pathology School of Dental Medicine Assessing mechanisms of neuronal death (apoptosis vs necrosis in response to neuroinflammotry mechanisms and oxidative stress and protection by neurotrophins to gain insight into the molecular mechanisms underlying neuronal loss in neurodegenerative Disorders (i.e. Alzheimer's Disease, Parkinson's disease, and HIV encephalitis). We are specifically interested in the role of cell cycle proteins and transcriptional regulators in neuronal survival decisions. |
| Michael Kahana, Ph.D. |
Professor
Department of Psychology,
University of Pennsylvania
Director, Computational Memory Lab
I am interested in human episodic memory for verbal, visual and spatial information. To study this general problem, I conduct experiments that measure behavioral and electrophysiological responses during memory tasks, and develop computational models to explain the resulting data. Our lab is one of several in the world studying the electrophysiological responses of neurons through direct intracranial electroencephalographic (iEEG) recording from the living human brain. Such recordings can be obtained from epilepsy patients who have had electrodes surgically implanted on the cortical surface of the brain or through the medial temporal lobes (including hippocampus) as part of the clinical process of localizing seizure foci. By analyzing how brain activity, including the responses of individual neurons, correlates with task variables, we are able to study the neurophysiological basis of memory with a high degree of spatial and temporal resolution. Current projects include studies of spatial navigation using a virtual taxi driver game, and computational modeling of the role of temporal context in visual and verbal memory.
| Matthew Lazzara, Ph.D. |
Assistant Professor of Chemical and Biomolecular Engineering
Assistant Professor of Bioengineering
Member, Institute of Medicine and Engineering
311A Towne Building
Cellular engineering, cell signaling, receptor-ligand interactions and trafficking, molecular therapeutics,
systems biology,and transport in biological systems
| Daniel Lee, Ph.D. |
Associate Professor
Dept. of Electrical and Systems Engineering
Dept. of Bioengineering (Secondary)
GRASP (General Robotics, Automation, Sensing, Perception) Lab
Machine learning, computational neuroscience, adaptive signal processing, robotics, embedded real-time
sensorimotor systems, multimodal sensory processing, motor learning, distributed multi-agent systems.
| Robert J. Levy, M.D. |
Professor of Pediatrics; Senior Scientist, Joseph Stokes, Jr. Research Institute,
Children's Hospital of Philadelphia
Interaction of biochemical concepts, pharmacology, pharmaceutics and biomaterials. Current projects in
the laboratory are concerned with mechanisms of cardiac valve and blood vessel calcification, localized
gene therapy for wound healing, myocardial implants for cardiac arrhythmia and primary syntheses of
therapeutic polymers for biomaterial use.
Resarch Associate Professor of Radiology
Computer technology for medical imaging, in particular, the formulation and computer
implementation of algorithms for image reconstruction from projection data, as derived
from transmitted x-rays or emitted gamma rays.
| Brian Litt, M.D. | |
Assistant Professor of Neurology |
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3 West Gates (215) 349-5166 |
My research focuses on my clinical work as a neurologist specializing in the care and
treatment of individualswith epilepsy.
| Edward J. Macarak, Ph.D. |
Professor of Anatomy and Histology, School of Dental Medicine
Professor of Bioengineering
4th Flr. Levy Building (215) 898-8993 |
Role of extracellular matrix in vascular, urologic and oral tissues. The role of mechanical
forces in altering the behavior of cells in these tissues.
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Assistant Professor of Radiology at the Hospital of the University of Pennsylvania 215 746-8763
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| Kenneth B. Margulies , M.D. |
Associate Professor of Medicine
Director, Cardiac Myocyte Core Lab
608 BRB II/III
Myocardial remodeling and reverse remodeling, Heart failure with preserved ejection fraction,
E-C coupling and regulation of contractility, Endogenous cardiac repair, Natriuretic peptide biology
| Susan S. Margulies, Ph.D |
Professor of Bioengineering
Chair Bioengineering Graduate Group
Member, Institute for Medicine and Engineering
105D Hayden Hall (215) 898-0882 |
Cell and tissue biomechanics, with emphasis on injury mechanisms and tolerances;
pulmonary regional ventilation and ventilator-induced injury; spinal cord injury; pediatric
and adult brain injury.
| Vadim Markel, Ph.D. |
Assistant Professor of Radiology
| Robert Mauck, Ph.D. | |
Assistant Professor of Orthopaedic Surgery Assistant Professor of Bioengineering |
|
| 424 Stemmler |
Engineering functional equivalents for musculoskeletal tissue engineering applications with particular focus on articular cartilage and meniscus. Mesenchymal stem cell mechanobiology and signal transduction in chondrogenic differentiation. Design of novel bioreactor systems to recapitulate the complex loading environment of diarthrodial joints.
Fabrication and application of anisotropic nanofibrous scaffold.
Professor of Bioengineering
Chair, Bioengineering
Member, Institute for Medicine and Engineering
105C Hayden Hall (215) 573-3155 |
Biomechanics of central nervous system injury; evaluation of automotive crash dynamics
and occupant restraints;experimental and computational modeling of brain and spinal cord
injury mechanics.
| Vladimir Muzykantov, M.D., Ph.D. |
Drug/gene targeting and vascular biology.
| Steven Nicoll, Ph.D. | |
Assistant Professor of Bioengineering |
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111 Hayden Hall (215) 573-2626 |
Connective tissue engineering, biomaterials, cartilage cell biology: Epigenetic Control of
Cellular Phenotype; Biomimetic Scaffolds for Connective Tissue Repair; Transcriptional
and Genetic Determinants of Chondrogenesis.
| Warren Pear, M.D., Ph.D. |
Tumor biology; signal transduction; leukemogenesis, including chronic myelogenous leukemia and
myeloproliferative diseases; hematopoietic stem cell, biology.
| Ravi Radhakrishnan, Ph.D. | |
Assistant Professor of Bioengineering |
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540 Skirkanich Hall (215) 898-0487 |
Computational biomolecular science and engineering, high performance computing, systems biology, carcinogenesis,
RNA catalysis, immunology.
| Ravinder Reddy, Ph.D. |
Development of sodium and proton MRI based diagnostic tools for detecting early degenerative changes in cartilage.
| Virginia M. Richards, Ph.D. |
Human Auditory Perception, Psycophysics, and Mathematical Psychology.
| Rahim Rizi, Ph.D. |
Associate Professor, Department of Radiology
The goal of our research group is to develop research and clinical techniques capable of
diagnosing a variety of pulmonary and metabolic disorders in their earliest stages,
and of evaluating the lung's response to therapy.
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Professor, RA-Radiology |
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Technical advances in medical imaging, especially MRI, functional neuroimaging, neonatal magnetoencephalopathy
| David Roos, Ph.D. |
Cell biology and molecular genetics of protozoan parasites: Toxoplasma and Plasmodium (malaria);
eukaryotic evolution; computational biology.
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Professor of Medicine |
The work in the lab is focused in three areas: elucidating the genetic and metabolic regulatory networks that allow tuberculosis to persist in the human host for years, determination of the molecular basis of serine protease inhibition and mathematical modeling of complex biomolecular systems.
| Casim A. Sarkar, Ph.D. | |
Assistant Professor of Bioengineering
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373 Towne Building (215)573-4072 |
Molecular cell engineering: rational design and directed evolution of proteins; cytokine/receptor
binding and trafficking; cell signaling and decision-making; computational, synthetic, and systems biology
| James C. Saunders, Ph.D. |
Professor of Neuroscience
The structure and function of the peripheral auditory system, the micro and macromechanics
of the middle ear, (tympanic membrane) and inner ear (hair cells); cellular activity in the
peripheral auditory nervous systems; mechanism of hair cell transduction; signal processing
in the cochlea; middle ear transmission.
| John C. Schotland, M.D., Ph.D. | |
Associate Professor of Bioengineering |
|
311 Hayden Hall (215) 898-8501 |
Optical tomography, near-field optics, inverse scattering, biomedical optics.
Professor& Director Ultrasound Research
Department of Radiology
University of Pennsylvania
215-349-5461
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Division of Neuropsychiatry 215-573-0278 |
Neurobiology of schizophrenia and development of new treatment modalities including long
term delivery systems.
| Douglas H. Smith, M.D. |
Associate Professor of Neurosurgery
Modeling focal and diffuse brain injury, post-traumatic cognitive dysfunction, and traumatic
axonal injury; techniques for diagnosis and treatment of brain trauma.
Assistant Professor, Department of Radiology
compensation; dynamic MRI; in vivo iron quantification using MRI.
| Louis J. Soslowsky, Ph.D. |
Professor of Orthopaedic Surgery
Professor of Bioengineering
Director of Orthopaedic Research
Member, Institute for Medicine and Engineering
424 Stemmler (215) 898-8653 |
Orthopaedic biomechanics and tissue engineering, soft tissue mechanics, shoulder
biomechanics, and joint biomechanics.
| Christian Stoeckert, Ph.D. |
Reseach Professor
Department of Genetics
Genomics unified schema used to itegrate sequence and its annotation from several sources
and structure in a database; understand gene regulation and build models for genetic networks.
| H. Lee Sweeney, PH.D. |
| William Maul Measey Professor and Chairman of Physiology |
Department of Physiology
B400 Richards Building
3700 Hamilton Walk
Molecular motors; muscle injury and disease; gene transfer into striated muscle;
myofibrillogenesis
| Phong Tran, Ph.D. |
Generation of positional information within cells by the cytoskeleton
| Andrew Tsourkas, Ph.D. |
Assistant Professor of Bioengineering
Assistant Professor of Radiology
Member, Institute of Medicine and Engineering
110 Hayden Hall (215) 898-8167 |
Development of novel molecular probes to image gene regulation, mRNA localization,
protein expression, and enzymatic activity in vivo using fluorescence, bioluminescence,
and magnetic resonance imaging approaches.
| Jayaram K. Udupa, Ph.D. |
Visualization and analysis of multi-dimensional biomedical images; computer graphics
for medical applications; kinematics of joints from image sequences; and volume rendering.
| Ragini Verma, Ph.D. |
Assistant Professor
Section of Biomedical Image Analysis, Radiology
Biomedical image analysis specifically multi-parametric Magnetic Resonance image analysis
and diffusion tensor imaging, facial expression analysis in neuropsychiatry
| Valerie M. Weaver, Ph.D. |
Member, Institute for Medicine and Engineering
Our laboratory studies the relationship between tissue architecture and the plasticity
of gene expression. The present objective of our work is to delineate the molecular
mechanisms driving malignant transformation of benign breast lesions, and to understand
the pathophysiology of multi-drug resistant, metastatic breast cancer.
| Felix W. Wehrli, Ph.D. |
Quantitative medical magnetic resonance imaging.
| Rebecca Wells , Ph.D. | |
| Assistant Professor, Depts of Medicine and Pathology and Laboratory Medicine |
|
| 215 573-1860 |
Liver fibrosis and in the mechanical and soluble factors (especially TGF-ß) that regulate liver fibrosis and the
phenotype of fibrogenic cells in the liver.
| Beth A. Winkelstein, Ph.D. | |
Associate Professor of Bioengineering Associate Professor of Neurosurgery Member, Institute of Medicine and Engineering |
|
108 Hayden Hall (215) 573-4589 |
Biomechanics of painful neck injuries; mechanical and cellular mechanisms of pain onset
and persistence; CNS neuroimmune responses of pain; cervical spine biomechanics;
understanding the role of injury mechanics in the physiology of pain.
| Arjun Yodh, Ph.D. |
James M. Skinner Professor of Science
Professor of Physics & Astronomy
Fundamental and applied condensed matter physics, biomedical optics & biophysics, and optical science.
Current research includes: soft materials, complex fluids & networks, carbon nanotubes, optical microscopy
& micromanipulation, biomedical optics, functional imaging & spectroscopy of living tissues, photodynamic
therapy and nonlinear optics.
Research Associate Professor
Radiology /Molecular Imaging Laboratory
Develop and implement molecular imaging approaches to study cancer and cardiovascular diseases.
Specific projects include stem cell based cardiac regeneration, cardiac kinematics using magnetic
resonance (MR) imaging based techniques, and study of tumor microenvironment by MR imaging and
spectroscopy.
Radiation Therapy and Photodynamic Therapy Physics
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