Solomon
R. Pollack, Ph.D.
spollack@seas.upenn.edu
Professor of Bioengineering; Professor of Orthopaedic Surgery
Research; Professor of Nursing
A.B., Physics, University of Pennsylvania, 1955
M.S., Physics, University of Pennsylvania, 1957
Ph.D., Physics, University of Pennsylvania, 1961
Research Interests
My research is concerned with the musculoskeletal system. We have
special interests in the bioelectrical properties of bone and connective
tissue; the electrical stimulation of bone growth and fracture healing;
electrokinetic effects in bone; biomaterials, hydroxyapatite, and
implants; and fluid flow effects on bone cells and their relationship
to bone tissue engineering. We also do research on tissue engineering
of bone graft material in rotating bioreactors. We have introduced
new technologies for 3-D scaffolds in bone tissue engineering that
facilitates earlier matrix synthesis and calcification. These technologies
combined with the use of rotating bioreactors offers the opportunity
to advance this field to the point of clinical trials.
Selected Publications
What is the Role of the Convective Current Density in the Real-Time
Calcium Response of Cultured Bone Cells to Fluid Flow? J. of Biomechanics;
29:1403-1409 1996.
Serum Plays a Critical Role in Modulating Cytosolic Calcium Concentration
of Primary Culture Bone Cells Exposed to Weak Ion Resonance Magnetic
Fields. BEMS 18:203-214, 1997.
Biochemical Pathway Mediating the Response of Bone Cells to Capacitively
Coupling. C.O.R.R.; 350: 246-256, 1998.
Streaming Potentials in Bone. Bone Biomechanics Handbook, CRC Press.
Edited by Stephen C. Cowin, in press.
3-D Self assembled scaffolds in a rotating bioreactor. Submitted
to Journal Tissue Engineering.
Bioengineering
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