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Credit: 1 course unit
Required course (Sophomore year)
Catalog
description:
An examination of the structure of property, performance
relationship for materials used in surgical implants and medical
devices. Consideration is given to issues of biocompatibility,
degradation of materials by biological systems, and biological response
to artificial materials. Particular attention will be given to the
materials of the total hip prosthesis and their relationship to the
long-term outcomes for total hip arthoplasty.
Prerequisites:
BE209, Chem 101, Corequisites:
BE210
Textbook(s) and/or
other required materials:
Callister, Materials Science and Engineering, An Introduction 6th
Ed.
Supplementary Materials:
·
Ratner, Hoffman,
Schoen & Lemons, Biomaterials Science: An Introduction to
Materials in Medicine 2nd Ed.
·
Park &
Lakes, Biomaterials: An Introduction 2nd Ed.
·
Finerman et al., Total
Hip Arthroplasty Outcomes
·
Buckwalter et al, Orthopaedic Basic Science 2nd
ed.
Course Objectives:
This course will provide a fundamental introduction to materials
used for biomedical applications, focusing on both atomic structure and
macroscopic bulk properties of the major classes of materials, as well as
issues of biocompatibility and biological responses to implantable
materials. As such, students are expected to gain a basic level
understanding of the materials selection and design criteria required for
engineering living tissue equivalents.
The course will consist of an introduction to materials science
and engineering, focusing on traditional classes of materials used for
biomedical applications (i.e., metals, ceramics, polymers, and
composites). Students will be
exposed to the multidisciplinary nature of biomaterials as the course
will incorporate aspects of materials science and engineering, the life
sciences. The course will also allow students to develop an appreciation
for important design criteria relevant to the biomedical implant
industry.
Topics Covered:
·
Atomic
Bonding in Solids
·
Structure
of Crystalline Solids
·
Imperfections
in Solids
·
Dislocations
& Strengthening
·
Mechanisms
·
Diffusion
·
Mechanical
Properties
·
Corrosion
& Degradation
·
Failure
·
Phase
Diagrams
·
Phase
Transformations
·
Thermal
Processing of Metal Alloys
·
Metal
Alloys
·
Ceramics
·
Processing
of Ceramics
·
Polymer
Structures
·
Processing
of Polymers
·
Composites
Class/Laboratory
schedule:
Lecture – 3 hr/week
Recitation – 1 hr/week
Contribution
towards Program Outcomes:
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Multidisciplinary
Ability
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High
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Problem Solving Approach
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High
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Problem Solving
Methods
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Med.
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Experimentation
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Low
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Design
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Low
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Professional
Orientation
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Low
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Contribution
towards Professional Component:
100% Engineering science
Person preparing
description and date:
William Graham
June 2005
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