|
Credit:
1
course unit
Elective course
Catalog
Description
Introduction to cell and molecular biology with
emphasis on quantitative concepts and applications to multicellular systems
Prerequisites: Graduate standing or
permission of instructor
Textbook(s) and/or Other Required Materials:
Required:
Molecular Biology of the Cell. Alberts et al., 4th Edition
Garland
Press
Recommended:
Biological Physics. Philip Nelson, WH Freeman and Co.
Mechanics of the Cell. David Boal, Cambridge Univ. Press
Course
Objectives:
The objective of this course is to integrate
structure with function at the molecular level. With emphasis on cellular
structures, students are introduced to the major tissue types found in
the human body and the kinds of specialized cells which comprise them.
Specialized functions and proteins associated with each of these tissues
are examined in detail at the molecular level. The cellular mechanisms
associated with ion transport, cell adhesion, cell division, DNA, RNA and
protein synthesis are explored in detail as well as relevant control
mechanisms involving signal transduction and intracellular signaling. The
role of the immune system is investigated as well as its molecular
regulation. The function of growth factors in altering cell behavior is
examined with emphasis on the cellular response to these types of
signals.
Topics
Covered:
Basic concepts; Techniques and Terminology in
Cell Biology Cellular Biochemistry; Cell Structures and Organelle
Function; Protein Structure and Function; DNA Synthesis; RNA
Transcription; Membrane Structures and Receptors; Protein Translation; Gene
Regulation; Cytoskeleton; Connective Tissue; Immunology; Nervous System;
Molecular Motors and Cell Motility; Cell Adhesion and Signaling;
Mechanical Stimulation of cells in vitro; Functional Genomics; Tissue
Engineering; Gene Therapy; Cardiovascular System
Class/Laboratory
Schedule:
Lecture: 3 hr/week
Contribution
towards Professional Component:
100% Engineering science
Contribution
towards Program Outcomes:
|
Multidisciplinary
Ability |
High |
|
Problem Solving
Approach |
Med. |
|
Problem Solving
Methods |
Low. |
|
Experimentation |
Med. |
|
Design |
Low |
|
Professional
Orientation |
Low. |
Person(s) Preparing
Description and Date:
Paul Janmey
July 2007
|
