BE517   Optical Imaging

Bioengineering Undergraduate Program

 

 

 

 

Credit:  1 course unit

 

Elective course

 

Catalog Description:

 

A modern introduction to the physical principles of optical imaging with biomedical applications. Propagation and interference of electromagnetic waves. Geometrical optics and the eikonal. Plane-wave expansions, diffraction and the Rayleigh criterion. Scattering theory and the Born approximation. Introduction to inverse problems. Multiple scattering and radiative transport. Diffusion approximation and physical optics of diffusing waves. Imaging in turbid media. Introduction to coherence theory and coherence imaging. Applications will be chosen from the recent literature in biomedical optics.

 

Prerequisites: EE 310 and EE 325 or equivalent

 

Textbook(s) and/or Other Required Materials:

 

Class notes, handouts and papers.

 

Course Objectives and Relationship to Program Educational Objectives:

 

This course is taught at the graduate level and may be taken as a senior-level elective for bioengineering majors. The goal is to provide a rigorous introduction to the mathematical and physical principles of biomedical optical imaging.

 

Topics Covered:

 

·        Review of Maxwell's equations, boundary conditions, conservation laws

·        Vector and scalar wave equations, integral theorems, Huygen's principle

·        Geometrical optics and the eikonal, interference, refraction

·        Plane-wave expansions, diffraction, Rayleigh criterion

·        Scattering, optical theorem, Born approximation

·        Introduction to inverse problems, Radon transform, inverse scattering and imaging in transparent media, applications to computational microscopy

·        Multiple scattering and the radiative transport equation

·        Diffusion approximation, boundary conditions

·        Physical optics of diffusing waves, applications to photodynamic therapy

·        Imaging in turbid media, applications to diffusion tomography

·        Introduction to coherence theory

·        Coherence imaging, applications to optical coherence tomography

·         

 Class/Laboratory Schedule:

 

Lecture: 3 hr/week

 

Contribution towards Professional Component:

 

100% Engineering science

 

Contribution towards Program Outcomes:

 

Multidisciplinary Ability

Med.

Problem Solving Approach

High

Problem Solving Methods

Low

Experimentation

Low

Design

Low

Professional Orientation

Low

 

Person Preparing Description and Date:

 

John Schotland
July 2007