Susan Margulies Named a Fellow of BMES

October 14, 2009

Susan MarguliesPHILADELPHIA –- Susan Margulies, Professor of Bioengineering, has been named a Fellow of the Biomedical Engineering Society for her national and international contributions to Biomedical Engineering and for inspired leadership in BMES. Fellowship is conferred by the Board of Directors to Society members who demonstrate exceptional achievements and experience in the field of biomedical engineering, and a record of membership and participation in the Society.

Margulies' research goal is to determine functional and structural injury thresholds in the brain and lung, and use them to understand mechanisms of traumatic brain and lung injury. In addition, her labs study of the biochemical and molecular biology of injured cells facilitates the development of preventive and therapeutic measures. Cells within the body routinely tolerate deformations during activities such as head turning and breathing, yet when cells are deformed beyond a safe limit or injury threshold, function and structure are altered temporarily or even permanently. Because human tissues tend to be inhomogeneous, anisotropic and nonlinear, and the tissues of interest undergo large strains, determining the complex relationship between cellular and macroscopic responses requires an integrated biomechanics approach consisting of several simultaneous rigorous engineering experimental and theoretical analyses. Tissue mechanical properties and injury thresholds are measured and used to develop computational models. These models are used to generalize the experimental cell and tissue findings and determine macroscopic injury mechanisms. Applications of current work are in the areas of traumatic head injury in adults and children, and ventilator-induced lung injury. These studies parallel clinical investigations regarding the treatment and detection of traumatic injury. For more information on her research, please visit

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