Class: BE210
Group: R4
Members: FACILITATOR Michael Kohanski, TIME & TASK KEEPER Brendon Tavelli,SCRIBE Brendon Tavelli, PRESENTER Laura Kaplan
Date: 5/11/00
Full Text

Abstract:

The three criteria for the successful fulfillment of the experimental goals were satisfied for aspartic acid.  First, clear separation of the experimentally determined pKa values was observed. The experimental values were 2.132 ± 0.164 and 3.602 ± 0.098 for pKa1 and pKa2, respectively. The lack of overlap within the 95% confidence intervals was sufficient to illustrate distinct pKa values.  Secondly, the precision of the values; pKa1 = 2.132 + 2.772% and pKa2 = 3.602 ± 2.680%, indicates that the procedure provides reproducible results.  Lastly, the pre-established limit for accuracy (3%) was achieved for pKa1, 2.132 ± 2.824%, and the accuracy of the pKa2 value fell within an acceptable range, 3.602 ± 6.677%.  Thus, this procedure is a valid method for the determination of close pKa values.