Most cited

1.      P. Ducheyne, Q.-Q. Qiu, Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function (Review), Biomaterials, 20, 2287-2303 (1999)

2.     P. Ducheyne, S. Radin, L. King, The effect of calcium phosphate ceramic composition and structure  on in vitro behavior :  I Dissolution.  J. Biomed. Mater. Res., 27, 25-34 (1993)

3.     P. Ducheyne, W. Van Raemdonck, J.C. Heughebaert, M. Heughebaert; Structural analysis of hydroxyapatite coatings on titanium, Biomaterials, 7, 97-103, 1986

4.     S. Radin, P. Ducheyne, The effect of plasma sprayed induced changes in characteristics on the in vitro stability of calcium phosphate ceramics, Mat. in Med., 3, 33-42 (1992)

5.     P. Ducheyne, S. Radin, M. Heughebaert, J.C. Heughebaert; The effect of structure and composition on the electrophoretic deposition, vacuum sintering and in vitro dissolution behavior of calcium phosphate ceramic coatings on metallic porous surfaces, Biomaterials, 11, 244-254 (1990)

6.     P. Ducheyne, L.L. Hench, A. Kagan, M. Martens, J.C. Mulier, A. Burssens; The effect of hydroxyapatite impregnation on bonding of porous coated implants, J. Biomed. Mat. Res. 14:225-237, 1980.

7.     S. Radin, P. Ducheyne, The effect of calcium phosphate ceramic composition and structure on in vitro behavior: II Precipitation.  J. Biomed. Mater. Res., 27, 35-45 (1993)

8.     G.K. Toworfe, R.J. Composto, I.M. Shapiro, P. Ducheyne, Nucleation and growth of calcium phosphate on amine-, carboxyl- and hydroxyl-silane self assembled monolayers, Biomaterials, 27, 631-642 (2006)

9.     K. Healy, P. Ducheyne, Hydration and preferential molecular adsorption on titanium in vitro.  Biomaterials, 13, 553-561 (1992)

10.  E. Schepers, M. DeClercq, P. Ducheyne, R. Kempeneers, Bioactive glass particulate material as a filler for bone lesions.  Oral Rehabilitation, 18, 439-452 (1991)

11.   T. Topoleski, P. Ducheyne and J.C. Cuckler; A fractographic analysis of in vivo poly(methylmethacrylate) bone cement failure mechanisms, J. Biomed. Mater. Res., 24, 135-154 (1990)

12.  S. Radin, G. El-Bassyouni, E.J. Vresilovic, E. Schepers, P.Ducheyne, In vivo tissue response to resorbable silica xerogels as controlled release materials, Biomaterials, 26, 1043-1052 (2005)

13.  K. Ishikawa, S. Radin, P. Ducheyne, Determination of the Ca/P ratio in Ca-deficient hydroxyapatite using x-ray diffraction analysis.  Mater. in Med., 4, 165-168 (1993)

14.  P. Ducheyne, Bioceramics:  Materials Characteristics vs In vivo Behavior, J. Appl. Biomat., 21, 219-236, (1987)

    15. T. Livingston, P. Ducheyne, J. Garino, The combination of osteoprogenitor cells and a bioactive ceramic scaffold promote bone repair, J. Biomed. Mater. Res., 62, 1-13 (2002)         


Publications regarding  Biocompatible, Inorganic  Controlled Release Materials Concepts

1.      H. Qu, M.C. Costache, S. Inan, A. Cowan, D. Devore, P. Ducheyne, Local, Controlled Delivery of Local Anesthetics in vivo from Polymer - Xerogel Composites, Pharm. Res. 33(3), 729-738 (2016)  

2.     H. Qu, S. Bhattacharyya, P. Ducheyne, Silicon oxide based materials for controlled release in orthopaedic procedures, Advanced Drug Delivery Reviews, 94 (2015) 96–115 (Invited review)

3.     H Qu, C. Knabe, S. Radin, J. Garino, P. Ducheyne, Prevention of Pin Tract Infection in External Fixation using Bactericidal Micron-Thin Sol-Gel Films, Biomaterials, 62 95-105 (2015)

4.     R. Cheng, H. Qu, A. S. Guo, P. Ducheyne, The design and synthesis of a soluble composite silica xerogel and the short-time release of proteins, J. Materials Chemistry B, 3, 3141-3149 (2015)

5.     H. Qu, S. Radin, P. Ducheyne, Release kinetics from porous xerogels in relationship to sol-gel synthesis variations and their resultant porous structure, Advanced Biomaterials and Devices in Medicine, 1, 11-17  (2014)

6.     H Qu, C. Knabe, M. Burke, S. Radin, J. Garino, T. Schaer, P. Ducheyne, Bactericidal Micron-Thin Sol-Gel Films Prevent Peri-Prosthetic and Pin Tract Infection, J. Military Medicine, 179, issue 8 (Suppl), 29-33 (2014)

7.     S. Bhattacharyya, A. Agrawal, C. Knabe, P. Ducheyne, Sol-gel silica controlled release thin films for the inhibition of methicillin resistant staphylococcus aureus, Biomaterials, 31, 509-517 (2014)

8.     S. Radin, S. Bhattacharyya, P. Ducheyne, Nanostructural control of the release of macromolecules from silica sol gels, Acta Biomaterialia, 9, 7987-7995 (2013), doi:

9.     M. Costache, A. Vaughan H. Qu, P. Ducheyne , D. Devore, Tyrosine-Derived Polycarbonate-Silica Xerogel Nanocomposites for Controlled Drug Delivery, Acta Biomateriala,9, 6544–6552 (2013),

10.  R. Cheng, H. Qu, A. Agrawal, S. Guo, P. Ducheyne, Controlled release of small molecules from silica xerogel with limited nanoporosity, J. Mat. Sci.: Mat. Medicine, 24, 137-146 (2013),

11.   S. Bhattacharyya, H. Wang, P. Ducheyne, Polymer coated mesoporous silica nanoparticles for the controlled release of macromolecules, Acta Biomateriala, 8, 3429-3435 (2012),

12.  M. Costache, H. Qu, P. Ducheyne , D. Devore, Polymer - Xerogel Composites for Controlled Release Wound Dressings, Biomaterials 31, 6336-6343 (2010)

13.  C.S. Adams, V. Antoci Jr., G. Harrison, P. Patal, T.A. Freeman, I.M. Shapiro, J. Parvizi, N.J. Hickock, S. Radin, P. Ducheyne, Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis, J. Orthop. Res., 27,701-709 (2009)

14.  S. Radin, T. Chen, P. Ducheyne, Emulsified sol-gel silica microspheres for controlled drug delivery, Biomaterials, 30, 850-858 (2009)

15.  S. Radin, P. Ducheyne, Controlled release of vancomycin from thin sol–gel films on titanium alloy fracture plate material, Biomaterials, 28, 1721-1729 (2007)

16.  W. Lai, J. Garino, C. Flaitz, P. Ducheyne, Excretion of resorption products from bioactive glass implanted in rabbit muscle, J. Biomed. Mater. Res., 75A, 398-407 (2005)

17.  S. Radin, G. El-Bassyouni, E.J. Vresilovic, E. Schepers, P.Ducheyne, In vivo tissue response to resorbable silica xerogels as controlled release materials, Biomaterials, 26, 1043-1052 (2005)

18.  S. Radin, S. Falaize, M.H. Lee, P. Ducheyne, In vitro bioactivity and degradation behavior of silica xerogels intended as controlled release materials, Biomaterials, 23, 3113-3122 (2002).

19.  W. Lai, J. Garino, P. Ducheyne, Silicon excretion from bioactive glass implanted in rabbit bone, Biomaterials, 23, 213- 217 (2002)

20. W. Aughenbauch, S. Radin, P. Ducheyne, Silica sol gel for the controlled release of antibiotics: II The effect of synthesis parameters on the in vitro release kinetics of Vancomycin, J. Biomed. Mater. Res., 57, 321-326 (2001)

21.  S. Radin, P. Ducheyne, T. Kamplain, B.H. Tan, Silica sol gel for the controlled release of antibiotics: I Synthesis, characterization and in vitro release, J. Biomed. Mater. Res., 57, 313-320 (2001)

22. S. Falaize, S. Radin and P. Ducheyne, In vitro behavior of silica-based xerogels intended as controlled release carriers, J. Am. Ceram. Soc., 82, 969-976 (1999)

23. E.M. Santos, S. Radin, B. Shenker, I. Shapiro, P. Ducheyne, Si-Ca-P xerogels and bone morphogenetic protein act synergistically on rat stromal marrow cell differentiation in vitro, J. Biomed. Mater. Res., 41, 87-94, (1998).

24. S.B. Nicoll,  S. Radin, E.M. Santos, R.S. Tuan, P. Ducheyne, In vitro release kinetics of biologically active transforming growth factor 1 from a novel xero-gel carrier , Biomat., 18, 853-859 (1997)

25. S. Radin, J. Campbell, J.M. Cuckler, P. Ducheyne, Calcium phosphate ceramic coatings as carriers of vancomycin, Biomaterials, 18, 777-782 (1997)


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