GCB535/CIS535 Introduction to BioInformatics

Fall term, 2004

Schedule

Announcements

[12/8/04] Grade statistics for everything except part II of HW6 and the second midterm.

[12/3/04] Midterm review session I will be Monday 12/6 from 5-6:30 in the regular classroom Towne 303.

Midterm review session II will be Wednesday during class.

The midterm is Friday 12/10 from 2-3p in our normal classroom, Towne 303.

[12/1/04] Homework 6 is in two parts. We will be going over proteomics tools in lab. No section this week, but at least one of the TAs will stay after lab to answer any homework questions. There will be a section at 1pm on Friday in Levine 612 to answer any questions. Check the announcements for word on a midterm review session scheduled for next Monday.

Archived announcements

Course Description:

The course covers methods used in computational biology, including the statistical models and algorithms used and the biological problems which they address. Students will learn how tools such as BLAST work, and will use them to address real problems. The course will cover sequence analysis problems such as exon, motif and gene finding, comparative methods, gene expression and (briefly) proteomics.

Course Description:

The course covers methods used in computational biology, including the statistical models and algorithms used and the biological problems which they address. Students will learn how tools such as BLAST work, and will use them to address real problems. The course will cover sequence analysis problems such as exon, motif and gene finding, comparative methods, gene expression and (briefly) proteomics.

This course has significant overlap with GCB531, Genome Science, but differs in stressing the hands-on use of bioinformatics tools, and having much less coverage of the biology side of genomics.

Schedule

Coordinator

Other Instructors:

Teaching Assistants:

Prerequisites

Knowledge of biology at the level of a good modern undergraduate course. Computer Sciences should review Larry Hunter's introduction to molecular biology for the computer scientist to get a feeling for the level of biology they should know (or be willing to quickly learn).

Course Requirements and Grading:

There will be roughly seven homeworks and two midterms. The homeworks will count for 50% of the grade, the midterms for 25% each. There will be no final exam.

Late Homework Penalty

Homework should be submitted at the beginning of class (2 pm) on the day that it is due. Homework received after the start of class will be penalized as follows:
15% reduction if 0-24 hours late
30% reduction if 24-48 hours late
45% reduction if 48-72 hours late
no credit if more than 3 days late

Textbook

D.W. Mount, Bioinformatics: Sequence and Genome Analysis, 2nd edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2004

Online Resources