Addition to HW2. Also due Friday. Since you are doing so well. :) 1. BLAST CLOCK against the the default database ("nr") in ncbi. (just type gi|4758010) into the "search" window and click "BLAST". human genome. Then click "FORMAT" on the page that comes up. Then wait a minute. You should get roughly 107 hits. Click on "Taxonomy reports" to see these organized by species. i) Homo sapiens has 20 hits. What's going on here? ii) Drosophila melanogaster has 10 hits. Which is the ortholog to CLOCK? iii) Drosophila pseudo-obscura only has 1 hit. Why does it have one when melanogaster has 10? 2. Circadian rhythms are, we have seen, deeply conserved, but the above query found nothing more remote than insects. Why not? How could you look further away evolutionarily? 3. Look at CLOCK in the USCS browser. Does the display help you see more about the conservation? If so, what do you see?