CIS/GCB 535 Final Project & Paper Example questions: group patients into risk categories based on gene expression data group genes into potential functionally similar groups based on gene expression data analyze conservation of a small number of genes across multiple species look for transcription factor binding sites (TFBSs) in a set of co-regulated genes look for common motifs in relatively small sequences (e.g. from Chip-chip data) It *is* acceptable to replicate work that has been done by someone else; you might also want to apply the method from one paper to another data set. Projects can be done individually or in teams of two. For the project proposal, please hand in a brief (1 page) description of what you propose to do, including 1) what question you will address 2) what data you will use 3) what method you will apply 4) what software you will use 5) references to two papers which applied similar methods to similar data sets You might start by looking for (5). Your final paper should describe the question being addressed the methods used to address the question the data used your results an analysis of the results including, as apprpriate, ROC curves references