Nuzhat Motlekar, M.S.
Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Bachelor of Pharmacy, 1998, University of Mumbai
M Tech.(Bioprocess technology), 2000, Institute of Chemical Technology (UICT), University of Mumbai
The research focus is on the discovery of novel chemical probes which can be used to further our understanding of disease mechanisms and/or may be useful in developing treatments for the same. This is accomplished by screening our 230K chemical library against various targets.
Biochemical screening - Assay development and screening in 384 and 1536 well formats against biologically relevant targets involved in cancer, cardiovascular disease and infection.
Cell-based screening - Development of 384 and 1536-well based screens for a wide variety of targets including cell-signaling pathways, chondrogenesis, siRNA screening, viral entry assays etc.