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Mechanobiology
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Joel Outten

Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Tel: 215-573-5704
Email:outten@seas.upenn.edu

Education

B.S. Engineering Science, Mathematics, University of Tennessee, 2002

M.S. Engineering Science, University of Tennessee, 2005

Research Projects

Single Nucleotide Gene Targeting

Single nucleotide gene targeting can be used to both correct and induce mutations within genes.  The therapeutic or experimental possibilities of this technique would be maximized by inducing these alterations within embryonic stem cells.  This technique has traditionally proven difficult.  I am currently focused on ways of improving the practicality and efficiency of these techniques.  We are working towards boosting the efficacy of this procedure up to the point where therapy development would be feasible.

 

 

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    Institute for Medicine & Engineering (IME)
    3340 Smith Walk
    1020 Vagelos Research Laboratories
    University of Pennsylvania
    Philadelphia, PA 19104-6383
    Lab No.: (215) 573-5704
    Fax: (215) 573-7227