spacer Institute of Medicine & Engineering (IME) spacer|spacer Biotech spacer|spacer BE spacer|spacer CBE spacer|spacer Penn Center for Molecular Discovery spacer|spacer Blood Systems Biology spacer
   
   
arrow Home
spacer spacer
arrow Director
spacer spacer
arrow Laboratory/Directions
spacer spacer
arrow Members
spacer spacer
arrow Alumni
spacer spacer
arrow News
spacer spacer
arrow Calendar
spacer spacer
arrow Publications
spacer spacer
arrow Research
 

Mechanobiology
Thrombolysis
Coagulation
Bioadhesion
Gene Therapy
Drug/Device
Proteomics
Drug Discovery
Systems Biology
Microfluidics

spacer spacer
arrow Pubmed
spacer spacer
arrow Cell Lines
spacer spacer
arrow Pubchem
 
   

Andrew Dolan

Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Tel: 215-746-4571
Email: adolan@seas.upenn.edu

Education

M.S., Chemical and Biomolecular Engineering, University of Pennsylvania, 2010
B.S., Chemical Engineering, Johns Hopkins University, 2008

Research Projects

Computational modeling of platelet calcium signaling

Research Summary
I am working on modeling how platelets respond to external stimuli. Using Monte Carlo sampling techniques we are able to characterize how different resting configurations affect the platelet's subsequent response to an activating signal. In particular we have developed a working model for the process of store-operated calcium entry which functions with parameters and displays dynamic behavior that is consistent with observations reported in scientific literature.

 

 

spacer Institute of Medicine & Engineering (IME) spacer|spacer Biotech spacer|spacer BE spacer|spacer CBE spacer|spacer EMTM spacer|spacer Penn Center for Molecular Discovery spacer|spacer Blood Systems Biology spacer


    Institute for Medicine & Engineering (IME)
    3340 Smith Walk
    1020 Vagelos Research Laboratories
    University of Pennsylvania
    Philadelphia, PA 19104-6383
    Lab No.: (215) 573-5704
    Fax: (215) 573-7227