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Mechanobiology
Thrombolysis
Coagulation
Bioadhesion
Gene Therapy
Drug/Device
Proteomics
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Microfluidics

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Ryan Muthard

Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Tel: 215-573-3025
Email: rmuthard@seas.upenn.edu

Education

B.S., Chemical Engineering, Pennsylvania State University, 2010

Research Projects

The main focus of my research has been to understand the complex interactions that thrombus development has with local hemodynamic forces and biological stimuli.  In order to study these interactions I designed a novel microfluidic device capable of independently controlling the wall shear stress and transthrombus pressure gradient, two physical parameters critical for thrombus development.  This device has facilitated investigations such as platelet and platelet/fibrin clot permeability, intra-clot thrombin localization, and mechanisms involved in thrombus contraction.

 

 

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    Institute for Medicine & Engineering (IME)
    3340 Smith Walk
    1020 Vagelos Research Laboratories
    University of Pennsylvania
    Philadelphia, PA 19104-6383
    Lab No.: (215) 573-5704
    Fax: (215) 573-7227