Litt Lab
1. Wulsin DF, Gupta JR, Mani R, Blanco JA, Litt B. Modeling electroencephalography waveforms with semi-supervised deep belief nets: fast classification and anomaly measurement. J Neural Eng. 2011 Apr 28;8(3):036015. [Epub ahead of print] NIHMSID: NIHMS294971 PubMed
2. Kim DH, Lu N, Ghaffari R, Kim YS, Lee SP, Xu L, Wu J, Kim RH, Song J, Liu Z, Viventi J, de Graff B, Elolampi B, Mansour M, Slepian MJ, Hwang S, Moss JD, Won SM, Huang Y, Litt B, Rogers JA. Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy. Nat Mater. 2011 Apr;10(4):316-23. NIHMSID: NIHMS284489
3. Stacey WC, Krieger A, Litt B. Network recruitment to coherent oscillations in a hippocampal computer model. J Neurophysiol. 2011 Apr;105(4):1464-81. PMCID: PMC3075292.
4. Viventi J, Blanco J, Litt B. Mining terabytes of submillimeter-resolution ECoG datasets for neurophysiologic biomarkers. Conf Proc IEEE Eng Med Biol Soc. 2010;1:3825-6. NIHMSID: NIHMS274926. PubMed
5. Blanco JA, Stead M, Krieger A, Viventi J, Marsh WR, Lee KH, Worrell G, Litt B. Unsupervised Classification of High-Frequency Oscillations in Human Neocortical Epilepsy and Control Patients. J Neurophysiol. 2010 Nov;104(5):2900-12. PMCID: PMC2997042. PubMed
6. Stead S, Bower M, Brinkmann B, Lee K, Marsh R, Myer F, Litt B, VanGompel J, Worrell, G. Microseizures and the Spatiotemporal Scales of Human Partial Epilepsy. Brain. 2010;133(9):2789-97. PMC: PMCID2929333
7. Viventi J, Kim DH, Moss J, Kim Y-S, Blanco J, Anetta N, Hicks A, Xiao J, Huang Y, Callans DJ, Rogers JA, Litt B. A Conformal, Bio-interfaced Class of Silicon Electronics for Mapping Cardiac Electrophysiology. Sci. Transl. Med. 2010; 2(24): 24ra22. PMCID: PMC3039774.
8. van Vugt MK, Schulze-Bonhage A, Litt B, Brandt A, Kahana MJ. Hippocampal Gamma Oscillations Increase with Memory Load. J Neurosci. 2010;30(7):2694-9. PMCID: PMC2835496
9. Marsh ED, Peltzer B, Brown Iii MW, Wusthoff C, Storm Jr PB, Litt B, Porter, BE. Interictal EEG spikes identify the region of electrographic seizure onset in some, but not all, pediatric epilepsy patients. Epilepsia. 2010; 51(4): 592-601. PMCID: PMC2907216.
10. Kim DH, Viventi J, Amsden J, Xiao J, Vigeland L, Kim Y-S, Blanco J, Frechette E, Contreras D, Kaplan D, Omenetto F, Huang Y, Hwang K-C, Zakin M, Litt B, Rogers JA. Dissolvable Films of Silk Fibroin for Ultrathin, Conformal Bio-Integrated Electronics. Nat Mater. 2010 Jun;9(6):511-7.
PMCID: PMC3034223.
11. Jacobs J, Korolev IO, Caplan JB, Ekstrom AD, Litt B, Baltuch G, Fried I, Schulze-Bonhage A, Madsen JR, Kahana MJ. Right-lateralized Brain Oscillations in Human Spatial Navigation. J Cogn Neurosci. 2010; 22(5):824-36. PMCID: PMC2839416.
12. van Vugt MK, Schulze-Bonhage A, Sekuler R, Litt B, Brandt A, Baltuch G, Kahana, MJ. Intracranial electroencephalography reveals two distinct similarity effects during item recognition. Brain Res. 2009;1299:33-44. PMCID: PMC2763991.
13. Stacey WC, Lazarewicz MT, Litt B. Synaptic noise and physiological coupling generate high-frequency oscillations in a hippocampal computational model. J Neurophysiol. 2009;102(4):2342-57. PMCID: PMC2775383.
14. Qin L, Guo W, Litt B. A Time-Frequency Functional Model for
Locally Stationary Time Series Data. Journal of Computational and Graphical Statistics. 2009;18(3):675-693. PMCID: PMC2836603.
15. Kelley MS, Jacobs MP, Lowenstein DH, NINDS Epilepsy Benchmark Stewards. The NINDS epilepsy research benchmarks. Epilepsia. 2009; 50(3): 579-82. PMCID: PMC2874963.
16. Worrell GA, Gardner AB, Stead SM, Hu S, Goerss S, Cascino GJ, Meyer F B, Marsh R, Litt B. High-frequency oscillations in human temporal lobe: simultaneous microwire and clinical macroelectrode recordings. Brain. 2008;131(4):928-37. PMCID: PMC2760070.
17. Wiggins M, Saad A, Litt B, Vachtsevanos G. Evolving a Bayesian classifier for ECG-based age classification in medical applications, in Journal of Applied Soft Computing. 2008; 8(1):599-608. PMC- In Process. WigginsAppliedSoftComputing.pdf
18. Stacey WC, Litt B. Technology insight: neuroengineering and epilepsy- designing devices for seizure control. Nat Clin Pract Neurol. 2008;4(4):190-201. PMCID: PMC 2904395.
19. Snyder DE, Echauz J, Grimes DB, Litt B. The statistics of a practical seizure warning system. J Neural Eng. 2008;5(4):392-401. PMCID: PMC2888045.
20. Halpern CH, Samadani U, Litt B, Jaggi JL, Baltuch GH. Deep brain stimulation for epilepsy. Neurotherapeutics. 2008;5(1):59-67. PMCID: PMC2941772.
21. Wong S, Gardner AB, Krieger AM, Litt B. A stochastic framework for evaluating seizure prediction algorithms using hidden Markov models. J Neurophysiol. 2007;97(3):2525-32. PMCID: PMC2230664.
22. Sederberg PB, Schulze-Bonhage A, Madsen JR, Bromfield EB, Litt B, Brandt A, Kahana MJ. Gamma oscillations distinguish true from false memories. Psychol Sci. 2007;18(11):927-32. PMCID: PMC2897900
23. Litt B, Krieger A. Of seizure prediction, statistics, and dogs: a cautionary tail. Neurology. 2007;68(4):250-1.
24. Gardner AB, Worrell GA, Marsh E, Dlugos D, Litt B. Human and automated detection of high-frequency oscillations in clinical intracranial EEG recordings. Clin Neurophysiol. 2007;118(5):1134-43. PMCID: PMC2020804.
25. Firpi H, Smart O, Worrell G, Marsh E, Dlugos D, Litt B. High-frequency oscillations detected in epileptic networks using swarmed neural-network features. Ann Biomed Eng. 2007;35(9):1573-84.
26. Gardner AB, Krieger A, Vachtsevanos G, Litt B. One-Class Novelty Detection for Seizure Analysis from Intracranial EEG. Journal of Machine Learning Research. 2006;7:1025-44.
27. Dube C, Richichi C, Bender RA, Chung G, Litt B, Baram TZ. Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysis. Brain. 2006;129(4):911-22.
28. Stead M, Worrell GA, Litt B. Frequency and Dependence of Long Range Temporal Correlations in Human Hippocampal Energy Fluctuations. Complexity, 2005;10(5):35-44.
29. Lehnertz K, Litt B. The First International Collaborative Workshop on Seizure Prediction: summary and data description. Clin Neurophysiol. 2005;116(3):493-505.
30. Esteller R, Echauz J, D'Alessandro M, Worrell G, Cranstoun S, Vachtsevanos G, Litt, B. Continuous energy variation during the seizure cycle: towards an on-line accumulated energy. Clin Neurophysiol. 2005;116(3):517-26. PMCID: PMC2941767
31. D'Alessandro M, Vachtsevanos G, Esteller R, Echauz J, Cranstoun S, Worrell G, Parish L, Litt B. A multi-feature and multi-channel univariate selection process for seizure prediction. Clin Neurophysiol. 2005;116(3):506-16.
32. Worrell GA, Parish L, Cranstoun SD, Jonas R, Baltuch G, Litt B. High-frequency oscillations and seizure generation in neocortical epilepsy. Brain. 2004;127(Pt 7):1496-506.
33. Parish LM, Worrell GA, Cranstoun SD, Stead SM, Pennell P, Litt B. Long-range temporal correlations in epileptogenic and non-epileptogenic human hippocampus. Neuroscience. 2004;125(4):1069-76.
34. Kerrigan JF, Litt B, Fisher RS, Cranstoun S, French JA, Blum DE, Dichter M, Shetter A, Baltuch G, Jaggi J, Krone S, Brodie M, Rise M, Graves N. Electrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy. Epilepsia. 2004;45(4):346-54.
35. Witte H, Iasemedis L, Litt B, Guest Editors. Editorial. Special Issue on Epileptic Seizure Prediction. Special Issue of IEEE Transactions on Biomedical Engineering. 2003;50(5):537-9.
36. Niederhauser JJ, Esteller R, Echauz J, Vachtsevanos G, Litt B. Detection of seizure precursors from depth-EEG using a sign periodogram transform. IEEE Trans Biomed Eng. 2003;50(4):449-58.
37. Litt B. Evaluating devices for treating epilepsy. Epilepsia. 2003;44 Suppl 7:30-7.
38. D'Alessandro M, Esteller R, Vachtsevanos G, Hinson A, Echauz J, Litt B. Epileptic seizure prediction using hybrid feature selection over multiple intracranial EEG electrode contacts: a report of four patients. IEEE Trans Biomed Eng. 2003;50(5):603-15.
39. Worrell GA, Cranstoun SD, Echauz J, Litt B. Evidence for self-organized criticality in human epileptic hippocampus. Neuroreport. 2002;13(16):2017-21.
40. Litt B, Lehnertz K. Seizure prediction and the preseizure period. Curr Opin Neurol. 2002;15(2):173-7.
41. Litt B, Echauz J. Prediction of epileptic seizures. Lancet Neurol. 2002;1(1)22-30.
42. Cranstoun SD, Ombao HC, von Sachs R, Guo W, Litt B. Time-frequency spectral estimation of multichannel EEG using the Auto-SLEX method. IEEE Trans Biomed Eng. 2002;49(9):988-96.
43. Valmadrid C, Voorhees C, Litt B, Schneyer CR. Practice patterns of neurologists regarding bone and mineral effects of antiepileptic drug therapy. Arch Neurol. 2001;58(9):1369-74.
44. Litt B, Baltuch G. Brain Stimulation for Epilepsy. Epilepsy & Behavior. 2001;2:S61-S67.
45. Litt B, Esteller R, Echauz J, D'Alessandro M, Shor R, Henry T, Pennell P, Epstein C, Bakay R, Dichter M, Vachtsevanos G. Epileptic seizures may begin hours in advance of clinical onset: a report of five patients. Neuron. 2001;30(1):51-64.
McKeown M, McNamara J. When do epileptic seizures really begin?
Accompanying editorial. Neuron. 2001;30(1):1-3.
46. Esteller R, Vachtsevanos G, Echauz J, Litt B. A Comparison of Waveform Fractal Dimension Algorithms. IEEE Transactions on Circuits & Systems. 2001;48(2):177-83.
47. Silverman IE, Berman, DM, Dike GL, Sung GY, Litt B, Wityk RJ. Vertebrobasilar dolichoectasia associated with Marfan syndrome. J Stroke Cerebrovasc Dis. 2000;9:196-8.
48. Epstein CM, Woodard JL, Stringer AY, Bakay RA, Henry TR, Pennell PB, Litt B. Repetitive transcranial magnetic stimulation does not replicate the Wada test. Neurology. 2000;55(7):1025-7.
49. Litt B, Wityk RJ, Hertz SH, Mullen PD, Weiss H, Ryan DD, Henry TR. Nonconvulsive status epilepticus in the critically ill elderly. Epilepsia. 1998;39(11):1194-202.
50. Wityk RJ, Lehman D, Klag M, Coresh J, Ahn H, Litt B. Race and sex differences in the distribution of cerebral atherosclerosis. Stroke. 1996;27(11):1974-80.
51. Webber WR, Litt B, Wilson K, Lesser RP. Practical detection of epileptiform discharges (EDs) in the EEG using an artificial neural network: a comparison of raw and parameterized EEG data. Electroencephalogr Clin Neurophysiol. 1994;91(3):194-204.
52. Webber WR, Litt B, Lesser RP, Fisher RS, Bankman I. Automatic EEG spike detection: what should the computer imitate? Electroencephalogr Clin Neurophysiol. 1993;87(6):364-73.
53. Litt B. Dipoles and the EEG. American Journal of EEG Technology. 1991;31:119-21.
54. Hansen B, Ko HW, Fisher, RS, Litt B. Practical Limits on the Biomagnetic Inverse Process Determined From InVitro Measurements in Spherical Conducting Volumes. Physics in Medicine and Biology. 1988;33(1):105-11.
Book:
Wilbourn A, Litt B, Isley M, Krauss G, Shields R, Levin K, Electroencephalography and Evoked Potentials. Electromyography/ Electroencephalography Vol. VII: SpaceLabs Medical;1994.
Editorials, Reviews, Book Chapters:
1. Fisher RS, Litt B., Stacey WC. Deep Brain Stimulation for Epilepsy. In: Winn RH, editor. Youman’s Neurological Surgery. 2011; In press.
2. Maus D, Litt B. Modern Electrocorticography. In: Baltuch G, Villemure JG, editors. Operative Techniques in Epilepsy Surgery: Thieme; 2009.
3. Echauz J, Wong S, Litt B. Seizure Analysis and Detection In Vivo. In: Baraban S, editor. Animal Models of Epilepsy: Methods and Innovations; Series: Neuromethods: Humana Press Inc.; 2009.
4. Krieger D, Litt B. Seizure Prediction: Its Evolution and Therapeutic Potential. In: Shorvon SD, Pedley T, editors. Blue Book of Neurology: the epilepsies 3. Philadelphia: Saunders; 2008.
5. Echauz J, Wong S, Smart O, Gardner A, Worrell G, Litt B. Quantitative methods for tracking seizure generation in epileptic networks. In: Soltesz I, Staley K, editors. Computational Neuroscience in Epilepsy: Elsevier; 2008.
6. Lehnertz K, Le Van Quyen M, Litt B. Seizure Prediction: A Comprehensive Review. In: Pedley T, Engel J Jr, editors. Epilepsy, A Comprehensive Textbook. 2nd ed. Philadelphia: Lippincott, Williams & Wilkins; 2008.
7. Litt B, Cranstoun S. EEG Engineering Principles. In: Pedley, Ebersole, editors. Current Practice of Clinical Electroencephalography. N.Y.: Raven Press; 2003.
8. Litt B, Cranstoun S. Recording from Anterior Nucleus of the Thalamus. In: Luders H, editor. Brain Stimulation for Epilepsy. London: Martin-Dunitz; 2003.
9. Kolb S, Litt B. Epilepsy in the Intensive Care Unit and Emergency Room. In: Devinsky O, Ettinger A, editors. Managing Epilepsy and Co-Existing Disorders: Butterworth – Heinemann; 2002. p. 515-34.
10. Glosser G, Litt B. Non-epileptic Seizures. In: Johnson R, Griffin J, McArthur J, editors. Current Therapy in Neurology. Philadelphia: B.C. Decker; 2001. p. 58-60.
11. Burgess R, Bej M, Brenner R, Gotman J, Jacobs E, Kelm G, et al. Technological Requirements for Long-Term Monitoring. In: Luders H, Comair Y, editors. Epilepsy Surgery. 2nd ed. NY: Lippincott, Williams & Wilkins; 2000.
12. Litt B, Krauss GL. Pharmacologic Approach to the Acute Seizure Patient. In: Chernow B, editor. Pharmacologic Approach to the Critically Ill Patient. 2nd ed. 1993. p. 484-506.
13. Litt B, Fisher R. EEG Engineering Principles. In: Daly, Pedly, editors. Current Practice of Clinical Electroencephalography. Second Edition ed. N.Y.: Raven Press; 1990.
Granted Patents
1. Echauz J, Esteller R, Litt B, Vachtsevanos G, inventors; Unified probabilistic framework for predicting and detecting seizure onsets in the brain and multitherapeutic device. U.S. 2008.
2. Esteller R, Echauz J, Litt B, Vachtsevanos G, inventors; Adaptive Method and Apparatus for Forecasting and Controlling Neurological Disurbances Under a Multi-Level Control. U.S. 2006.
3. Echauz J, Esteller R, Vachtsevanos G, Litt B, inventors; Unified Probabilistic Framework for Predicting and Detecting Seizure Onsets in the Brain and Multitherapeutic Device. U.S. 2004.
4. Litt B, Vachtsevanos G, Echauz J, Esteller R, inventors; Method and Apparatus for Predicting the Onset of Seizures Based on Features Derived From Signals Indicative of Brain Activity. U.S. 2003.
5. Esteller R, Echauz J, Vachtsevanos G, Litt B, inventors; Adaptive Method and Apparatus for Forecasting and Controlling Neurological Disturbances Under a Multi-Level Control. U.S. 2003.
