Pulmonary Fluid Mechanics Laboratory - Publications

Biofluid Mechanics with special interests in liquid, gas, particle, and heat flow in the human respiratory system.







Key Publications

SCHREINER M.S., SCHERER P.W. Microembolic Reduce Phase III Slopes of CO2 and Invert Phase III Slopes of Infused SF6. Resp. Physiol., pp. 137-154 (1993).

KEYHANI K. Numerical modeling of airflow and mass transfer in the human nasal cavity, Doctoral Thesis. University of Pennsylvania, Philadelphia, PA.(1995).

KEYHANI K., SCHERER P.W. AND MOZELL M.M. Numerical simulation of airflow in the human nasal cavity, Transactions of the ASME Journal of Biomechanical Engineering , 117: 429-441 (1995).

HAHN I., SCHERER P.W. AND MOZELL M.M. A mass transport model of olfaction, Journal of Theoretical Biology , 167: 115-128 (1994).

PYON K.H. Odorant transport in a large scale bullfrog nasal cavity model, Doctoral Thesis. University of Pennsylvania, Philadelphia, PA.(1994).

SCHWARDT J.D., NEUFELD G.R., BAUMGARDNER J.E. AND SCHERER P.W. Noninvasive recovery of acinar anatomic information from CO2 expirograms, Annals of Biomedical Engineering , 22: 293-306 (1994).

HAHN I., SCHERER P.W. AND MOZELL M.M. Velocity profiles measured for airflow through a large-scale model of the human nasal cavity, Journal of Applied Physiology , 75: 2273-2287 (1993).

HAHN I. Modeling Nasal Airflow and Olfactory Mass Transport, Doctoral Thesis. University of Pennsylvania, Philadelphia, PA.(1992).

NEUFELD G.R., SCHWARDT J.D., GOBRAN S.R., BAUMGARDNER J.E., SCHREINER M.S., AUKBURG S.J. AND SCHERER P.W. Modelling steady state pulmonary elimination of He, SF6 and CO2: effect of morphometry, Respiration Physiology , 88: 257-275 (1992).

NEUFELD G.R., GOBRAN S., BAUMGARDNER J.E., AUKBURG S.J., SCHREINER M. AND SCHERER P.W. Diffusivity, respiratory rate and tidal volume influence inert gas expirograms, Respiration Physiology , 84: 31-47 (1991).

SCHWARDT J.D., GOBRAN S.R., NEUFELD G.R., AUKBURG S.J. AND SCHERER P.W. Sensitivity of CO2 washout to changes in acinar structure in a single-path model of lung airways, Annals of Biomedical Engineering , 19: 679-697 (1991).

SCHWARDT J.D., NEUFELD G.R. AND SCHERER P.W. Sensitivity of phase III slope to FRC and breathing pattern in a single-path airway model, (1991).

NEUFELD G.R., BAUMGARDNER J.E. AND SCHERER P.W. Interpreting expired CO2 waveforms [letter; comment], Anesthesia & Analgesia , 71: 711-712 (1990).

SCHERER P.W., NEUFELD G.R., AUKBERG S.J. AND GOBRAN S. Computer modeling of gas phase O2 airway transport, Advances in Experimental Medicine & Biology , 277: 647-652 (1990).

SCHERER P.W., HAHN I.I. AND MOZELL M.M. The biophysics of nasal airflow, Otolaryngologic Clinics of North America , 22: 265-278 (1989).

SCHERER P.W., MULLER W.J., RAUB J.B. AND HASELTON F.R. Convective mixing mechanisms in high frequency intermittent jet ventilation, Acta Anaesthesiologica Scandinavica Supplementum , 90: 58-64 (1989).

SCHERER P.W., GOBRAN S., AUKBURG S.J., BAUMGARDNER J.E., BARTKOWSKI R. AND NEUFELD G.R. Numerical and experimental study of steady-state CO2 and inert gas washout, Journal of Applied Physiology , 64: 1022-1029 (1988).

PERSONS D.D., HESS G.D. AND SCHERER P.W. Maximization of pulmonary hygroscopic aerosol deposition, Journal of Applied Physiology , 63: 1205-1209 (1987).

PERSONS D.D., HESS G.D., MULLER W.J. AND SCHERER P.W. Airway deposition of hygroscopic heterodispersed aerosols: results of a computer calculation, Journal of Applied Physiology , 63: 1195-1204 (1987).

HANNA L.M. AND SCHERER P.W. Regional control of local airway heat and water vapor losses, Journal of Applied Physiology , 61: 624-632 (1986).

HANNA L.M. AND SCHERER P.W. A theoretical model of localized heat and water vapor transport in the human respiratory tract, Transactions of the ASME Journal of Biomechanical Engineering , 108: 19-27 (1986).

HANNA L.M. AND SCHERER P.W. Measurement of local mass transfer coefficients in a cast model of the human upper respiratory tract, Transactions of the ASME Journal of Biomechanical Engineering , 108: 12-18 (1986).

SCHERER P.W. Mechanisms of gas transport during high frequency ventilation, Medical Instrumentation , 19: 195-198 (1985).

SCHERER P.W., HASELTON F.R. AND SEYBERT J.R. Gas transport in branched airways during high-frequency ventilation, Annals of Biomedical Engineering , 12: 385-405 (1984).

SCHERER P.W., NEUFELD G.R., AUKBURG A.J. AND HESS G.D. Measurement of effective peripheral bronchial cross section from single-breath gas washout, Transactions of the ASME Journal of Biomechanical Engineering , 105: 290-293 (1983).

SCHERER P.W. AND HASELTON F.R. Convective exchange in oscillatory flow through bronchial-tree models, Journal of Applied Physiology , 53: 1023-1033 (1982).

SCHERER P.W. Mucus transport by cough, Chest , 80: 830-833 (1981).

SCHERER P.W. AND HASELTON F.R. Mass transport in a bronchial bifurcation model, (1980).

SCHERER P.W. AND HASELTON F.R. A network theory of bronchial gas mixing applied to single breath nitrogen washout, Lung , 158: 201-220 (1980).

SCHERER P.W. AND HASELTON F.R. Convective mixing in tube networks, AIChE Journal , 25: 542-544 (1979).

SCHERER P.W., HASELTON F.R., HANNA L.M. AND STONE D.R. Growth of hygroscopic aerosols in a model of bronchial airways, Journal of Applied Physiology: Respiratory, Environmental & Exercise Physiology , 47: 544-550 (1979).

SCHERER P.W. AND BURTZ L. Fluid mechanical experiments relevant to coughing, Journal of Biomechanics, 11: 183-187 (1978).

SCHERER P.W., SHENDALMAN L.H., GREENE N.M. AND BOUHUYS A. Measurement of axial diffusivities in a model of the bronchial airways, Journal of Applied Physiology , 38: 719-723 (1975).

SCHERER P.W. Flow in axisymmetrical glass model aneurysms, Journal of Biomechanics , 6: 695-700 (1973).

SCHERER P.W., SHENDALMAN L.H. AND GREENE N.M. Simultaneous diffusion and convection in single breath lung washout, Bulletin of Mathematical Biophysics , 34: 393-412 (1972).

SCHERER P.W. A model for high Reynolds number flow in a human bronchial bifurcation, Journal of Biomechanics , 5: 223-229 (1972).


Hayden Hall Pulmonary Fluid Mechanics Laboratory
3320 Smith Walk, Hayden Hall #19,
Department of Bioengineering
University of Pennsylvania
Philadelphia, PA 19104
Phone 215-898-7214
Fax 215-573-2071