Resize the outer container:

3231 Walnut St., Philadelphia PA 19104

Polymer Physics


Polymer Nanocomposites: Nanorod Dispersion in Polymer Thin Films


Self-Assembly of Polymer Nanorod Composite Films
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR09-07493))

 


Monte Carlo simulations of Au nanorod dispersion/aggregation in thin films.
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR09-07493))

 


Au Nanorods in PS-b-PMMA films: Confinement, ordering, and phase transitions.
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR09-07493))

Polymer Nanocomposites: Dynamics


Molecular Dynamics in Nanocomposites with Controlled Particle-Brush
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR12-10370))

 


Macromolecular Diffuion in Polymer Nanocomposites Having Attracive Interaction
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR12-10370))

 

Biopolymer Science


Cell Injection


 

Cell injection is one of the core methods to introduce non-permeable molecules into cells. It allows direct access to the two main intracellular compartments, the nucleus and cytoplasm. The video above shows dye (for visualization) being injected into human dermal fibroblast cells. Cell injection is used in conjunction with AFM and other biophysical imaging techniques to connect the viscoelasticity of cells to overall cell health.

 

Stimuli-responsive Surfaces


"A stimuli-responsive, controlled release bilayer for the prevention of bacterial infection on biomaterials" (A) Bacterial infection on biomaterials involves (I) bacterial attachment, (II) bacterial colonization and biofilm formation, and (III) biofilm detachment for bacterial proliferation. (B) pH-responsive, drug release polymer bilayer system has an outer layer of chitosan (CH, biopolymer, blue), which provides biocompatibility and hemocompatibity in direct contact with biological tissue. An inner layer of poly(acrylic acid) (PAA, synthetic polymer, red) is grown from the biomaterial. The depicted drug release mechanism is that bacterial colonization and formation of a biofilm on the tobramycin (TOB, yellow)-loaded CH/PAA bilayer causes a local decrease in pH near the infected area (B.II). The reduced local pH triggers the outer CH layer to swell and reduces the electrostatic attraction between PAA and TOB (B.III). TOB loaded in PAA releases and diffuses into biofilm to kill the bacteria (B.IV).

 

Nanogel Carriers


 

Dextrain and lysozyme hybrid nanogel doped with stable silver nanoparticles as a study of drug delivery systems.

 

Nanomechanics of Cells


 

Cartoon depicting the method by which Myosin V processivity is used to elucidate the effect of nanocomposite surface immobilization on the ability of actin filaments to support motility.
(This material is based upon work supported by the National Science Foundation under Grant Number (DMR08-3802))