Journals

M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, H Hamedani, S Siddiqui, K Ruppert, N Drachman, J Rajaei, R Rizi. In vivo imaging of the progression of acute lung injury using hyperpolarized [1‐13C] pyruvate. Magnetic Resonance in Medicine. January 2017 (link)

H Hamedani, S Kadlecek, Y Xin, S Siddiqui, H Gatens, J Naji, M Ishii, M Cereda, M Rossman, R Rizi.A hybrid multibreath wash‐in wash‐out lung function quantification scheme in human subjects using hyperpolarized 3He MRI for simultaneous assessment of specific ventilation, alveolar oxygen tension, oxygen uptake, and air trapping. Magnetic Resonance in Medicine. October 2016 (link)

S Siddiqui, S Kadlecek, M Pourfathi, Y Xin, W Manneherz, H Hamedani, N Drachman, K Ruppert, J Clapp, R Rizi. The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging. Advanced Drug Delivery Reviews. September 2016 (link)

H Hamedani, J Clapp, S Kadlecek, K Emami, M Ishii, W Gefter, Y Xin, M Cereda, H Shaghaghi, S Siddiqui, M Rossman, R Rizi. Regional Fractional Ventilation by Using Multibreath Wash-in 3He MR Imaging. Radiology. January 2016 (link)

H Shaghaghi, S Kadlecek, S Siddiqui, M Pourfathi, H Hamedani, J Clapp, H Profka, R Rizi. Ascorbic acid prolongs the viability and stability of isolated perfused lungs: A mechanistic study using 31P and hyperpolarized 13C NMR . Free Radical Biology and Medicine. December 2015 (link)

J Clapp, H Hamedani, S Kadleck, Y Xin, H Shaghaghi, S Siddiqui, M Rossman, R Rizi. Multibreath alveolar oxygen tension imaging. Magnetic Resonance in Medicine. October 2015 (link)

H Hamedani, H Shaghaghi, S Kadlecek, Y Xin, B Han, S Siddiqui, J Rajaei, M Ishii, M Rossman, R Rizi. Vertical gradients in regional alveolar oxygen tension in supine human lung imaged by hyperpolarized 3He MRI. NMR in Biomedicine. November 2014 (link)

S Kadlecek, H Shaghaghi, S Siddiqui, H Profka, M Pourfathi, R Rizi. The effect of exogenous substrate concentrations on true and apparent metabolism of hyperpolarized pyruvate in the isolated perfused lung. NMR in Biomedicine. October 2014 (link)

H Shaghaghi, S Kadlecek, C Deshpande, S Siddiqui, D Martinez, M Pourfathi, H Hamedani, M Ishii, H Profka, R Rizi. Metabolic spectroscopy of inflammation in a bleomycin-induced lung injury model using hyperpolarized 1-13C pyruvate. NMR in Biomedicine. May 2014 (link).

S Siddiqui, Y Xin, K Emami, J D'Armiento, T Shiomi, H Profka, P Mongkolwisetwara, R Rizi. Hyperpolarized 3He Diffusion MRI and Histology of Secreted Frizzled Related Protein-1 (SFRP1) Deficient Lungs in a Murine Model. Magnetic Resonance Imaging. February 2014 (link).

A Agarwal, S Kumar, J Narang, L Schultz, T Mikkelsen, S Wang, S Siddiqui, H Poptani, R Jain. Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression. Journal of Neuro-Oncology. February 2013 (link).

GJ Kazakia, D Kuo, J Schooler, S Siddiqui, S Shanbhag, G Bernstein, A Horvai, S Majumdar, M Ries, X Li. Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees. Osteoarthritis and Cartilage. September 2012 (link).

C McMillan, C Brun, S Siddiqui, M Churgin, D Libon, P Yushkevich, H Zhang, A Boller, J Gee, M Grossman.The Contribution of White Matter Neuroimaging to Multimodal Diagnosis of Frontotemporal Lobar Degeneration. Neurology. April 2012 (link).

E Jones, D Miller, H Wahnishe, J Schooler, S Siddiqui, X Li. Characterization of Human Osteoarthritic Cartilage Using Optical and Magnetic Resonance Imaging. Molecular Imaging and Biology. February 2012 (link).

K Shet, S Siddiqui (co-first author), H Yoshihara, J Kurhanewicz, M Ries, X Li. High-resolution magic angle spinning NMR spectroscopy of human osteoarthritic cartilage. NMR Biomed. August 2011 (link).

Conferences

S Siddiqui, M Pourfathi, A Habertheuer, Y Xin, H Hamedani, H Profka, A Naji, P Vallabhajosyula, R Rizi. Metabolic and Structural Imaging of Syngeneic and Allogeneic Rat Lung Transplantation. ATS: Washington D.C., USA (2016).

M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, H Hamedani, S Siddiqui, I Duncan, N Drachman and R Rizi. Investigating the Effects of Protective and Non­protective Ventilation After Acute Lung Injury Using Hyperpolarized [1­13C] Pyruvate. ATS: Washington D.C., USA (2016).

M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, H Hamedani, I Duncan, S Siddiqui, N Drachman and R Rizi. Combination of Pulmonary Lactate­to­Pyruvate and Compliance to Characterize the Severity and Progression of Acute Lung Injury Using Hyperpolarized [1­13C] Pyruvate MRI. ATS: Washington D.C., USA (2016).

S Siddiqui, M Pourfathi, N Drachman, S Kadlecek, Y Xin, H Profka, R Rizi. CT and Hyperpolarized Carbon­13 MR­based Multimodal Biomaker for Pulmonary Fibrosis in a Bleomycin Induced Lung Injury Model. ATS: Washington D.C., USA (2016).

N Drachman, S Siddiqui, M Pourfathi, S Kadlecek, R Rizi. Assessment of Lung Injury by MR Quantification of the Bicarbonate­to­Pyruvate Ratio in the Heart. ATS: Washington D.C., USA (2016).

Y Xin, M Cereda, H Hamedani, S Siddiqui, M Pourfathi, M Itkin-Ofer, S Turner, N Meeder, S Kadlecek, J Clapp, L Hughes, A Roberts, Q Bey, A Rodriguez, N Drachman, I Duncan, H Profka, N Tustison, J Gee, B Kavanagh, R Rizi. Parametric Response Maps to Measure the Effects of Prone Position in Pigs with Experimental Lung Injury. ATS: Washington D.C., USA (2016).

Y Xin, M Cereda, H Hamedani, S Siddiqui, M Pourfathi, M Itkin-Ofer, S Turner, N Meeder, S Kadlecek, J Clapp, L Hughes, A Roberts, Q Bey, A Rodriguez, I Duncan, N Drachman, H Profka, N Tustison, J Gee, B Kavanagh, R Rizi. Parametric Response Mapping Detects Distribution of Abnormal Lung Inflation in Pneumonia and Acid Aspiration. ATS: Washington D.C., USA (2016).

H Hamedani, S Kadlecek, Y Xin, M Cereda, S Siddiqui, M Pourfathi, N Drachman, M Rossman, R Rizi. A Multi­parametric Hyperpolarized Gas MR Imaging Map for Prediction and Monitoring of Lung Function Deterioration. ATS: Washington D.C., USA (2016).

M Cereda, Y Xin, H Hamedani, G Bellani, S Kadlecek, M Itkin-Ofer, J Clapp, L Guerra, N Meeder, S Turner, L Hughes, I Duncan, M Pourfathi, S Siddiqui, N Drachman, A Roberts, Q Bey, A Rodriguez, N Tustison, J Gee, B Kavanagh, R Rizi. Imaging Prediction of ARDS Outcome. ATS: Washington D.C., USA (2016).

S Siddiqui, M Pourfathi, A Habertheuer, Y Xin, H Profka, H Hamedani, S Kadlecek, A Naji, P Vallabhajosyula, R Rizi, “Metabolic characterization of rat lung transplantation using HP [1-13C]-pyruvate MRI. ISMRM: Honolulu, USA (2016).

M Pourfathi, Y Xin, M Cereda, S Kadlecek, H Profka, H Hamedani, I Duncan, S Siddiqui, N Drachman, K Ruppert, and R Rizi, “Probing metabolic alterations in lung injury during protective and non-protective ventilation using hyperpolarized [1-13C] pyruvate. ISMRM: Honolulu, USA (2016).

M Pourfathi, H Hamedani, Y Xin, S Kadlecek, M Cereda, H Profka, I Duncan, N Drachman, S Siddiqui, K Ruppert, J Naji and R Rizi . Regional Analysis of Hyperpolarized Lactate-to-Pyruvate Ratio Can Improve Sensitivity to Monitor Progression of Acute Pulmonary inflammation. ISMRM: Honolulu, USA (2016).

H Hamedani, M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, I Duncan, S Siddiqui, N Drachman, K Ruppert, R Rizi. A Multi-Variate Regional Study of Acute Lung Injury Using Hyperpolarized [1-13C] Pyruvate. ISMRM: Honolulu, USA (2016).

N Drachman, S Kadlecek, H Hamedani, M Pourfathi, S Siddiqui, Y Xin, H Profka, I Duncan, R Rizi. Assessing Gas Exchange via Co-Administration of Hyperpolarized [1-13C] Pyruvate and 13C-Bicarbonate. ISMRM: Honolulu, USA (2016).

H Hamedani, Y Xin, S Kadlecek, I Duncan, S Siddiqui, M Pourfathi, N Drachman, K Ruppert, J Naji, M Cereda, R Rizi. Multi-parametric Response Map Using Hyperpolarized Gas MR Imaging to Retain Regionality: Making Hyperpolarized Gas Imaging Great Again. ISMRM: Honolulu, USA (2016).

S Siddiqui, M Pourfathi, A Habertheuer, Y Xin, H Hamedani, A Naji, R Rizi. Multimodal Structural and Metabolic Imaging of Rat Lung Allotransplants 41st Annual Eugene P. Pendergrass Symposium (2016).

M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, S Siddiqui, H Hamedani, N Drachman, R Rizi. Imaging Metabolic Alterations in Acute Lung Injury using Hyperpolarized [1-13C] Pyruvate. 41st Annual Eugene P. Pendergrass Symposium (2016)

M Pourfathi, S Kadlecek, Y Xin, S Siddiqui, M Cereda, H Profka, H Hamedani, R Rizi. In vivo­quantitative assessment of lung injury using Carbon-13 HP-MRI in a two­hit model of acid aspiration and VILI. ATS: San Francisco, USA (2016)

S Kadlecek, Y Xin, H Hamedani, S Siddiqui, M Pourfathi, H Profka, R Rizi. Ventilation measurement using CT end­-inspiration/end-­expiration image comparison and a novel registration method. ATS: San Francisco, USA (2016)

H Hamedani, S Kadlecek, Y Xin, M Cereda, H Gatens, J Naji, S Siddiqui, M Pourfathi, M Rossman, R Rizi. Prediction of Future Lung Function Decline from Baseline Hybrid Hyperpolarized 3He MRI in Current Smokers and COPD Patients. ATS: San Francisco, USA (2016)

S Siddiqui, Y Xin, H Profka, S Kadlecek, R Rizi. Using MicroCT To Quantify The Compliance Of Lungs In A Bleomycin-Induced Pulmonary Fibrosis Rat Model. ATS: San Francisco, USA (2016).

M Cereda, Y Xin, S Kadlecek, J Zeng, A Rodriguez, H Staroba, N Meeder, Q Bey, H Profka, S Siddiqui, M Pourfathi, H Hamedani, R Rizi. Transient Receptor Potential Vanilloid Antagonism Alleviates the Propagation of Lung Injury. ATS: San Francisco, USA (2016)

M Pourfathi, Y Xin, S Kadlecek, M Cereda, H Profka, S Siddiqui, H Hamedani, R Rizi. In-vivo Assessment of Lung Injury Using Hyperpolarized Carbon-13 MRI in a Two-hit Model of Acid Aspiration and VILI. ISMRM: Singapore (2016)

M Pourfathi, S Kadlecek, H Profka, S Siddiqui, H Gatens, R Rizi. Towards High Resolution Chemical Shift Imaging of the Lungs using Hyperpolarized Carbon-13. ISMRM: Singapore (2016)

H Hamedani, Y Xin, S Kadlecek, H Gatens, M Cereda, S Siddiqui, M Pourfathi, J Naji, M Ishii, R Rizi. Prediction of Longitudinal FEV1 Decline in Smokers with Hybrid Hyperpolarized 3He MR. ISMRM: Singapore (2016)

H Shaghaghi, S Kadlecek, M Pourfathi, S Siddiqui, M Cereda, H Hamedani, H Profka, Y Xin, R Rizi. Detection of Lung Mitochondrial Dysfunction Using Hyperpolarized [1-13C] Pyruvate Metabolism. ISMRM: Toronto, Canada (2015)

H Shaghaghi, S Kadlecek, M Pourfathi, S Siddiqui, H Profka, H Hamedani, M Cereda, Y Xin, R Rizi. Hyperpolarized 1-13C Pyruvate Metabolism of Inflamed Lung via Pulmonary Delivery: A preliminary Study. ISMRM: Toronto, Canada (2015)

H Shaghaghi, Y Xin, S Siddiqui, S Kadlecek, M Pourfathi, H Profka, H Hamedani, M Cereda, Y Xin, R Rizi. Hyperpolarized 1-13C Pyruvate Metabolism as a Marker of Inflammation and Progression of Lung Injury. ISMRM: Toronto, Canada (2015)

Y Xin, H Hamedani, M Cereda, S Siddiqui, M Pourfathi, M Cereda, H Profka, H Hamedani, R Rizi. Hyperpolarized 1-13C Pyruvate Metabolism of Inflamed Lung via Pulmonary Delivery: A preliminary Study. ISMRM: Toronto, Canada (2015)

H Shaghaghi, M Pourfathi, S Siddiqui, S Kadlecek, H Profka, R Rizi. Ascorbate Increases Lung Viability and Energy Charge in Isolated Perfused Lungs. ATS: Denver, USA. ID #67372 (2015)

H Shaghaghi, S Kadlecek, M Pourfathi, S Siddiqui, Y Xin, H Hamedani, H Profka, M Cereda, R Rizi. Spectroscopy of Lung Inflammation via Pulmonary Delivery of Hyperpolarized [1-13C] Pyruvate: A Preliminary Study. ATS: Denver, USA. ID# 66657 (2015)

H Shaghaghi, S Kadlecek, S Siddiqui, M Pourfathi, H Profka, H Hamedani, R Rizi. Detection of ETC Complex I and IV Activity Using Hyperpolarized [1-13C] Pyruvate and 31P NMR Spectroscopy. ATS: Denver, USA. ID# 67006 (2015)

H Hamedani, S Kadlecek, Y Xin, S Siddiqui, M Pourfathi, M Cereda, M Rossman, R Rizi. Measuring Fractional Ventilation Using Hyperpolarized Helium-3 Multi-breath Technique in Human Subjects. ATS: Denver, USA. ID# 68292 (2015)

H Hamedani, S Kadlecek, Y Xin, S Siddiqui, M Pourfathi, M Cereda, M Rossman, R Rizi. Quantitative Imaging of Alveolar Recruitment with Hyperpolarized Xenon Diffusion MRI. ATS: Denver, USA. ID# 67588(2015)

H Hamedani, S Kadlecek, Y Xin, S Siddiqui, M Pourfathi, H Profka, M Cereda, R Rizi. The Comparison of Alveolar Oxygen Tension Measurement with Hyperpolarized Xenon-129 and Helium-3. ATS: Denver, USA. ID# 67520 (2015)

S Kadlecek, H Hamedani, Y Xin, S Siddiqui, M Pourfathi, H Profka, M Cereda, R Rizi. A Washin-Washout Hyperpolarized Gas MRI Technique to Measure Fractional Ventilation. ATS: Denver, USA. ID# 67456 (2015)

H Shaghaghi, S Kadlecek, S Siddiqui, Y Xin, M Cereda, M Pourfathi, H Hamedani, H Profka, R Rizi. Using hyperpolarized 1-13C pyruvate metabolism as marker of inflammation in acute lung injury. ATS: Denver, USA. ID# 66420 (2015)

H. Hamedani, S. Kadlecek, M. Ishii, M. Cereda, Y. Xin, H. Shaghaghi, S. Siddiqui, S. Zarrin, M. Rossman, R. Rizi. Reproducibility Study Of Hyperpolarized 3He Specific Ventilation In Human. ATS: San Diego, USA. Poster #A2398 (2014) (link).

H. Hamedani, M. Ishii, S. Kadlecek, Y. Xin, H. Shaghaghi, D. Gopstein, S. Siddiqui, M. Rossman, R. Rizi. Alveolar Oxygen Tension Measurements Using 3He MRI As A Tool In Diagnosis Of Difficult-To-Assess Functional Alterations In Asymptomatic Smokers. ATS: San Diego, USA. Poster #A5420 (2014) (link).

H. Shaghaghi, S. Kadlecek, M. Pourfathi, S. Siddiqui, H. Profka, R. Rizi. Vitamin C As A Potential Prophylactic Against Pulmonary Mitochondrial Dysfunction. ATS: San Diego, USA. Poster #A5769 (2014) (link).

H. Hamedani, S. Kadlecek, M. Ishii, Y. Xin, H. Shaghaghi, S. Siddiqui, M. Rossman, R. Rizi. Discriminating Smokers And Nonsmokers Using Helium-3 Imaging Derived Specfic Ventilation, Alveolar Oxygen Tension And Apparent Diffusion Coefficent Measurement. ATS: San Diego, USA. Poster #A6287 (2014) (link).

S. Kadlecek, H. Shaghaghi, M. Pourfathi, S. Siddiqui, J. Rajei, H. Profka, R. Rizi. Measurements and Modeling of Hyperpolarized 1-13C in the Perfused Lung in Relation to Organ Redox State. ISMRM: Milan, Italy. Poster #2775 (2014)

H. Hamedani, S. Kadlecek, M. Ishii, Y. Xin, H. Shaghaghi, B. Han, S. Siddiqui, S. Zarrin, M. Rossman, R. Rizi. Early Detection Of Smoking-Induced Pulmonary Alterations Using Hyperpolarized 3He MRI Derived Alveolar Partial Pressure of Oxygen. ISMRM: Milan, Italy. Poster #2276 (2014)

H. Shaghaghi, S. Kadlecek, M. Pourfathi, S. Siddiqui, H. Profka, R. Rizi. A Survey On The Effect Of Antioxidant And Metabolism Modifiers On Lung Metabolism Using Hyperpolarized 13C NMR. ISMRM: Milan, Italy. Poster #2789 (2014)

H. Hamedani, S. Kadlecek, M. Ishii, Y. Xin, H. Shaghaghi, B. Han, S. Siddiqui, M. Rossman, R. Rizi. A Preliminary Variability Study Of Hyperpolarized 3He Specific Ventilation In Human. ISMRM: Milan, Italy. Poster #2293 (2014)

H. Hamedani, S. Kadlecek, M. Ishii, Y. Xin, H. Shaghaghi, B. Han, S. Siddiqui, M. Rossman, R. Rizi. Assessing the Diagnostic Power of a Hybrid Combination of Hyperpolarized 3 He MRI derived ADC, Specific Ventilation and Alveolar Oxygen Tension in COPDs. ISMRM: Milan, Italy. E-poster #3533 (2014)

S. Siddiqui, M. Pourfathi, H. Hamedani, Y. Xin, H. Shaghaghi, S. Kadlecek, R. Rizi. Comparison of Calculated Specific Ventilation using the 'Wash-in' and 'Wash-out' Hyperpolarized 3 He MRI Techniques. ISMRM: Milan, Italy. E-poster #3535 (2014)

H. Shaghaghi, S. Kadlecek, S. Siddiqui, M. Pourfathi, H. Profka, R. Rizi. Ascorbic Acid Enhances Pyruvate Dehydrogenate Flux In Isolated Perfused Rat Lungs. ISMRM: Milan, Italy. E-poster #3804 (2014)

H Shaghaghi, S Kadlecek, H Profka, S Siddiqui, N Kuzma, M Ishii, R Rizi. The effect of hyperpolarized [1-13C] pyruvate concentration on lung metabolism. ATS: Philadelphia, USA. Poster (2013)

S Siddiqui, H Shaghaghi, S Kadlecek, H Profka, R Rizi. Metabolic spectroscopy and imaging of lung inflammation using hyperpolarized 1-13C pyruvate. ISMRM: Salt Lake City, USA. Poster #1932 (2013)

C McMillan, C Brun, S Siddiqui, M Churgin, D Libon, P Yushkevich, H Zhang, A Boller, J Gee, M Grossman. The Contribution of White Matter Neuroimaging to Multimodal Diagnosis of Frontotemporal Lobar Degeneration. AAN: New Orleans, LA, USA. Abstract #P03.096 (2012) (link)

G. Kazakia, D. Kuo, J. Schooler, S. Siddiqui, G. Bernstein, S. Shanbhag, A. Horvai, S. Majumdar, M. Ries, X. Li. Bone And Marrow Demonstrate Changes Localized to Bone Marrow Edema-like Lesions within Osteoarthritic Joints. ORS: Long Beach, CA, USA. Presentation #0212 (2011)

K. Shet, S. Siddiqui, J. Kurhanewicz, X. Li. Relaxation Parameters of N-acetyl in Healthy and Osteo-Arthritic Cartilage - An High Resolution Magic Angle Spinning (HR-MAS) Study. ISMRM: Stockholm, Sweden. Poster #873 (2010).

D. Kuo, J. Schooler, J. Goldenstein, S. Siddiqui, S. Shanbhag, J-B. Pialat, A. Burghardt, S. Majumdar, M. Ries, G. Kazakia, X.Li . Multi-Modality Imaging of Bone Marrow Edema-Like Lesions and Associated Cartilage in Osteoarthritic Patients. ISMRM: Stockholm, Sweden. Poster 801 (2010).

S. Siddiqui, R. Iman, J. Wooten, J. Kurhanewicz , M. Ries, and X. Li. HR-MAS Spectral Analysis of Osteoarthritic Cartilage. ISMRM: Honolulu, USA. Poster #1981 (2009).

J. Cheng, E. Saadat, R. Bolbos, B. Jobke, S. Siddiqui, M. Ries, T. Link, X. Li, and S. Majumdar. Detection of Proteoglycan Content in Human Osteoarthritic Cartilage Samples with Magnetic Resonance T1rho Imaging. ISMRM: Toronto, Canada. Presentation #326 (2008).



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