Penn Engineering

Chemical and Biomolecular Engineering (CBE)

A Student in CBE 4100

Shaping the Future of Biomolecular Engineering

At the intersection of innovation and discovery, Penn’s Department of Chemical and Biomolecular Engineering (CBE) redefines what’s possible in science and technology. Our programs are designed to empower students to tackle global challenges—from sustainable energy solutions to groundbreaking biomedical advancements. Here, transformative research and interdisciplinary collaboration spark solutions that shape the future.

Marylin Huff works with students in the CBE lab at Penn Engineering

Questions We Answer 

How can molecular-level innovations drive sustainability and global health? What breakthroughs in biomolecular engineering will transform medicine and energy systems? Our department challenges the status quo, empowering students to explore bold questions and redefine the possible.

 

Challenges We Solve 

Whether it’s developing renewable energy technologies or engineering life-saving therapeutics, we solve critical problems that affect the world at every scale. By bridging foundational research with real-world applications, we create solutions that advance healthcare, energy, and sustainability.

A student works in a CBE lab

Impact We Make 

CBE researchers and alumni pioneer advancements in biotechnology, sustainable manufacturing, and clean energy. From designing innovative materials to revolutionizing pharmaceutical processes, our work sets the standard for the technologies shaping tomorrow.

Opportunity We Have

With access to cutting-edge laboratories, collaborative initiatives across disciplines, and connections to industry leaders, our students are positioned to lead. At Penn, innovation is not just encouraged—it’s expected, offering students the tools to shape the future.

You might be interested in chemical and biomolecular engineering if:

  • You’re passionate about developing sustainable solutions for global challenges, like clean energy and reducing plastic waste.
  • You’re curious about how chemicals and biological systems interact to create new materials, medicines, and technologies.
  • You’re excited about engineering processes to produce life-saving vaccines, advanced biomaterials, or next-generation fuels.
  • You want to explore how nanotechnology and molecular-level innovations can transform industries ranging from healthcare to environmental science.
  • You’re motivated to make an impact by addressing pressing issues like climate change, global health disparities, and resource scarcity.
possible careers
  • Software Development Engineer II

    Harshmeet Singh, 2021 | Amazon Web Services
  • Principal Researcher

    Behnaz Arzani, 2016 | Microsoft
  • Research Engineer

    Jacob Kahn, 2018 | Facebook AI Research
  • Technical Staff

    Cam Nguyen, 2012 | Nutanix
  • Engineering Manager

    Connie Ho, 2013 | Meta
by the numbers
  • 5:1

    Undergraduate Student-to-Faculty Ratio
  • $ 7M

    in Annual Research Expenditures
  • 21

    Faculty Members
  • # 3

    National Academy of Engineering Members

Signature Courses

Students will understand, evaluate, and apply different equations of state relating pressure, temperature, and volume for both ideal and non-ideal systems. The course will focus on calculating and applying residual properties and departure functions for thermodynamic analysis of non-ideal gases. Students will apply and describe simple models of vapor-liquid equilibrium in multi-component systems (e.g. Raoult’s Law, modified Raoult’s Law, Henry’s Law). Additionally, the class will analyze and describe properties of non-ideal mixtures and their component species. We will also model and predict reaction equilibria (including non-ideal fluid systems), as well as solve problems related to complex phase equilibria of multi-component systems (find equilibrium compositions for non-ideal phases). Prerequisite required: CBE 2300 Material and Energy Balances of Chemical Processes.

This course introduces the principles of material and energy balances and their applications to the analysis of single- and multiple-phase processes used in the chemical, pharmaceutical, and environmental industries. The course focuses on the conceptual understanding of properties of pure fluids, equations of state, and heat effects accompanying phase changes and chemical reactions, and problem-solving skills needed to solve a wide range of realistic, process-related problems.

The design of industrial methods for separating mixtures. Distillation; liquid-liquid extraction; membranes; absorption. Computer simulations of the processes.

Design of chemical, biochemical, and materials products and processes based on recent advances in chemical and bioengineering technology. Design group weekly meetings with faculty advisor and industrial consultants. Comprehensive design report and formal oral presentation. Heat exchanger design and profitability analysis. Prerequisite required: CBE 4000 Intro to Product and Process Design.

Our Expert Faculty

Penn CBE faculty are trailblazers in sustainable energy, biopharmaceuticals, and advanced materials. Through groundbreaking research and dedicated mentorship, they empower students to address global challenges and excel in shaping the future of science and technology.

All CBE Faculty
Bomyi Lim

Bomyi Lim

Area of expertise: Gene Regulation, Imaging, Chemical Kinetics, Quantitative Biology

Students know me for: Being supportive, passionate about science, and committed to education

I want to make an impact in: Probing the regulatory logic of gene expression kinetics that lead to normal development

Daeyeon Lee Professor at Penn Engineering

Daeyeon Lee

Area of expertise: The study of soft materials, with a focus on their interfaces and their assembly into functional structures for healthcare and sustainability applications

Students know me for: Promoting a collaborative and inclusive environment

I want to make an impact in: Advancing scientific knowledge in soft matter systems and translating that into practical solutions for energy, environmental, and healthcare challenges

Aleksandra Vodjovic

Aleksandra Vojvodic

Rosenbluth Associate Professor
Chemical and Biomolecular Engineering