Research Expertise: Tissue Engineering | Orthopaedic Bioengineering | Biomaterials
Rob's research program focuses on the engineering of musculoskeletal tissues, with a particular focus on articular cartilage, the knee meniscus, and the intervertebral disc. His group uses rigorous mechanical and molecular analyses to understand the emerging functional properties of engineered tissues, to precisely define the criteria and routes toward 'success' from native tissue structure and function, and to focus technology development on improving these critical features in engineered constructs. Specifically, this work employs adult mesenchymal stem cells, custom mechanobiologic culture conditions, and novel scaffolding technologies to enhance and direct functional tissue development.
PhD Biomedical Engineering 2003 - Columbia University
- Measuring clinically relevant knee motion with a self-calibrated wearable sensor, Hullfish, T.J. | Qu, F. | Stoeckl, B.D. | Gebhard, P.M. | Mauck, R.L. | Baxter, J.R., Journal of Biomechanics, 2019
- Mechanically Activated Microcapsules for “On-Demand” Drug Delivery in Dynamically Loaded Musculoskeletal Tissues, Mohanraj, B. | Duan, G. | Peredo, A. | Kim, M. | Tu, F. | Lee, D. | Dodge, G.R. | Mauck, R.L., Advanced Functional Materials, 2019
- Cell migration: implications for repair and regeneration in joint disease, Qu, F. | Guilak, F. | Mauck, R.L., Nature Reviews Rheumatology, 2019
- Extracellular vesicles mediate improved functional outcomes in engineered cartilage produced from MSC/chondrocyte cocultures, Kim, M. | Steinberg, D.R. | Burdick, J.A. | Mauck, R.L., Proceedings of the National Academy of Sciences of the United States of America, 2019
- Nascent protein secretion directs cell mechanosensing and function in three-dimensional hydrogels, Loebel, C. | Mauck, R.L. | Burdick, J.A., Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, 2019