Christopher M. Madl Assistant Professor Chemical and Biomolecular Engineering Materials Science and EngineeringPrimary Research Website About Christopher Area of expertise: The design of hydrogel biomaterials to mimic the extracellular matrix Students know me for: Encouraging independent and creative thinking to help students mature as scientists in class and in the lab I want to make an impact in: Our understanding of the complex mechanisms of tissue dysfunction that occur during aging and disease Education Christopher Madl earned his BA and MS in Engineering Sciences from Harvard University in 2012 and received his PhD in Bioengineering from Stanford University in 2017. He was a postdoctoral fellow in Stem Cell Biology at Stanford University before joining the MSE faculty in 2022. Research The Madl laboratory develops new hydrogel materials to study the role of biophysical cues from the extracellular environment on tissue dysfunction in aging and disease. The lab employs protein engineering and stimuli-responsive bioorthogonal chemistries to make materials with on-demand tuning of mechanical and microstructural cues. The lab is particularly interested in how altered mechanical signals in aged skeletal muscle and nervous system tissues lead to impaired cellular function. Madl is a core faculty member of the Center for Precision Engineering for Health (CPE4H). He also holds a secondary appointment in Chemical and Biomolecular Engineering and is a member of the Bioengineering graduate group. Keywords: Materials for Health Science, Polymers and Soft Matter, Biomaterials, Hydrogels, Mechanobiology, Stem Cells, Disease Modeling Awards 2024 NIH R35 Maximizing Investigators’ Research Award (MIRA) 2021 NIH K99/R00 Pathway to Independence Award 2019 Life Sciences Research Foundation (LSRF) Postdoctoral Fellowship 2016 Siebel Scholars Class of 2017
