Reengineering AI to Target “Undruggable” Disease Proteins News / August 13, 2025 A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body — even when scientists don’t know what those proteins look like. The breakthrough could lead to new treatments for diseases that have... Read More
Engineering a Healthier Future: Kelsey Swingle’s Journey from Penn Student to Rice Faculty News / July 22, 2025 Kelsey Swingle (GrENG’25) has made a remarkable leap from doctoral training at Penn to a tenure-track faculty position at Rice University. Her pioneering work on lipid nanoparticle delivery of mRNA therapeutics targets critical women’s health issues like pre-eclampsia, addressing a major gap in reproductive medicine. Trained in the Mitchell Lab... Read More
Less Pain, More Gain: A New Recipe for Safer, Stronger mRNA Therapies News / July 18, 2025 As millions of people know firsthand, the most common side effect of mRNA vaccines like the COVID-19 shot is inflammation: soreness, redness and a day or two of malaise. But what if mRNA vaccines could be redesigned to sidestep that response altogether?In a new paper in Nature Biomedical Engineering, researchers... Read More
Engineering a Healthier Heart: Noor Momin Receives AHA Transformational Project Award News / July 17, 2025 When someone survives a heart attack, the battle isn’t always over. In fact, nearly one-third of survivors go on to develop heart failure—a progressive weakening of the heart muscle that affects millions and contributes to roughly 500,000 deaths in the U.S. each year. Dr. Noor Momin, the Stephenson Foundation Term... Read More
$2.6M NIH Grant Backs Search for Genetic Cure in Deadly Heart Disease News / July 7, 2025 Fourteen million people worldwide suffer from enlarged hearts, or hypertrophic cardiomyopathy (HCM), a genetic disease that thickens the heart’s walls, making it harder for the organ to pump blood — but many of them don’t know it. The disease is often undiagnosed, despite being the most common genetic heart disease... Read More
Spaces That Spark Discovery: A Look Inside One uCity Square News / January 14, 2025 Thoughtfully designed for light, flexibility and constant exchange, the new labs at One uCity Square are reshaping how precision-health research happens. Read More
