An In Vitro Study of the Effect of Blockage on Pressure in the Capillaries


Class: BE-310
Group: M4
Members: Andrew James, Siddharth Fernandes, Brian Fabella, Nick Rose
Date: 05/04/98
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Abstract:
The pressure changes for blocked and unblocked arteries were tested using a simulated capillary model. In order to simulate blood we used water and a sucrose solution, both of which correlated well with each other. The assumptions listed in our mathematical model allowed us to use the aforementioned fluids as a substitute for blood. A plot of pressure changes for the capillary manometers according to the blockage position was used to analyze the pressure changes for blocked and unblocked capillaries. Also a plot of pressure changes for the capillary manometers according to the blockage position for both water and sucrose solution was used to analyze pressure changes for blocked capillaries with water and sucrose solution. It is seen from the data obtained that the entrance pressure into the capillary model does not significantly change with a change in the blockage position. Also we have shown that that the capillaries in the path of the blockage exhibit an increased pressure as the blockage moves past the capillary in the direction of the flow.