Center for Bioactive Materials
and Tissue Engineering



 

©Journal of Biomedical Materials Research, 1995
The Center for Bioactive Materials and Tissue Engineering represents a multidisciplinary research group from the various departments in the School of Engineering and Applied Sciences, the School of Dentistry and the School of Medicine

Since the late 1980's when the challenge of in vitro synthesis of bone tissue was first addressed, the investigation of mechanistic effects of materials on cellular functions, specifically cell attachment, proliferation, differentiation and extracellular matrix formation, was at the core of the Center's program. Other studies have focused on the combined effects of microgravity and substrate material on cellular functions; the use of self assembled monolayer chemistry to create highly controlled surfaces; studying the effect of calcification of such surfaces on cell function; and the controlled release of growth factors, cytokines, antibiotics, etc. from bioactive, silica based sol gels. 
 


Facilities   Research Overview    Key References   Tissue Engineering of the Spine    Recent Publications      Calcified Surfaces     

Comments to: Paul Ducheyne -- ducheyne@seas.upenn.edu

page last updated 12/17/07