M. Guvendiren, M. Perepelyuk, R.G. Wells, J.A. Burdick, Hydrogels with Differential and Patterned Mechanics to Study Stiffness Mediated Myofibroblastic Differentiation of Hepatic Stellate Cells, in review.




W. Gramlich, J.L. Holloway, R. Rai, J.A. Burdick, Transdermal Gelation of Methacrylated Macromers with Near-infrared Light and Gold Nanorods, in review.




D.E. Soranno, H.D. Lu, H.M. Weber, R. Rai, J.A. Burdick, Immunotherapy with Injectable Hydrogels to Treat Obstructive Nephropathy, in review.




K. Ihada-Stansbury, J. Ames, S. Sanyal, N. Aiad, K.C. Kawabata, I. Levental, H.G. Sundararaghavan, K. Miyazono, J.A. Burdick, P. Janmey, R.G. Wells, P.L. Jones, The Homeobox Gene Transcription Factor Prx1 Regulates Pulmonary Vascular Smooth Muscle Cell Differentiation via its Control over Matrix Properties, in review.




S.R. Eckhouse, B.P. Purcell, J.R. McGarvey, D. Loeb, C.B. Logdon, H. Doviak, J. O’Neil, J. Schuman, C. Novak, K.N. Zellars, S. Pettaway, R. Mukherjee, J.H. Gorman, R.C. Gorman, R.A. Black, J.A. Burdick, F.G. Spinale, Local Hydrogel Release of Recombinant Tissue Inhibitor of Metalloproteinase-3 Attenuates Adverse Left Ventricular Remodeling after Myocardial Infarction, in revision.




M.I. Dishowitz, F. Zhu, H.G. Sundararaghavan, J.L. Ifkovits, J.A. Burdick, K.D. Hankenson, Jagged1 Immobilization to a Poly(b-amino ester) Polymer Activates the Notch Signaling Pathway and Induces Osteogenesis, Journal of Biomedical Materials Research A, in press.




L. Bian, M. Guvendiren, R.L. Mauck, J.A. Burdick, Hydrogels that Mimic Developmentally Relevant Matrix and N-cadherin Interactions Enhance MSC Chondrogenesis, Proceedings of the National Academy of Sciences (PNAS), in press.




J.W. MacArthur, B.P. Purcell, Y. Shudo, J.E. Cohen, A. Fairman, A. Trubelja, J. Patel, P. Hsiao, E. Yang, W. Hiesinger, P. Atluri, J.A. Burdick, Y.J. Woo, Sustained Release of Engineered Stromal Cell Derived Factor 1-alpha from Injectable Hydrogels Effectively Recruits Endothelial Progenitor Cells and Preserves Ventricular Functional Following Myocardial Infarction, Circulation, in press.




J.A. Shuman, J.R. Zurcher, Ashley A. Sapp, J.A. Burdick, R.C. Gorman, J.H. Gorman, E.C. Goldsmith, F.G. Spinale, Localized Targeting of Biomaterials following Myocardial Infarction: A Foundation to Build on, Trends in Cardiovascular Medicine, in press.




M. Guvendiren and J.A. Burdick, Engineering Synthetic Hydrogel Microenvironments to Instruct Stem Cells, Current Opinion in Biotechnology, in press.




H.D. Lu, D.E. Soranno, C.B. Rodell, I.L. Kim, J.A. Burdick, Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels, Advanced Healthcare Materials, in press.

I.L. Kim, S. Khetan, B.M. Baker, C.S. Chen, J.A. Burdick, Fibrous Hyaluronic Acid Hydrogels that Direct MSC Chondrogenesis through Mechanical and Adhesive Cues, Biomaterials, 34:5571-5580, 2013.




S. Khetan, M. Guvendiren, W.R. Legant, D.M. Cohen, C.S. Chen, J.A. Burdick, Degradation-mediated Cellular Traction Directs Stem Cell Fate in Covalently Crosslinked Three-dimensional Hydrogels, Nature Materials, 12:458-465, 2013.




D. Hanjaya-Putra, Y.I. Shen, A. Wilson, K. Fox-Talbot, S. Khetan, J.A. Burdick, C. Steenbergen, S. Gerecht, Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing, Stem Cells Translational Medicine, 2:297-306, 2013.




J.A. Burdick, R.L. Mauck, J.H. Gorman, R.C. Gorman, Acellular Biomaterials: An Evolving Alternative to Cell-Based Therapies, Science Translational Medicine, 5:176ps4, 2013.




H.G. Sundararaghavan, R.L. Saunders, D.A. Hammer, J.A. Burdick, Fiber Alignment Directs Cell Motility over Chemotactic Gradients, Biotechnology and Bioengineering, 110:1249-1254, 2013.




M. Guvendiren and J.A. Burdick, Stem Cell Response to Spatially and Temporally Displayed and Reversible Surface Topography, Advanced Healthcare Materials, 2:155-164, 2013.




L. Bian, C. Hou, E. Tous, R. Rai, R.L. Mauck, J.A. Burdick, The Influence of Hyaluronic Acid Hydrogel Crosslinking Density and Macromolecular Diffusivity on Human MSC Chondrogenesis and Hypertrophy, Biomaterials, 34:413-421, 2013.




J.S. Katz and J.A. Burdick, Synthetic Biomaterials, in The Biomedical Engineering Handbook, 4th Edition (eds. J. Fisher, A. Mikos, Tissue Engineering Section), CRC Press, 2013.

J.A. Burdick and W.L. Murphy, Moving from Static to Dynamic Complexity in Hydrogel Design, Nature Communications, 3:1269, 2012.




R.J. Wade and J.A. Burdick, Engineering ECM Signals into Biomaterials, Materials Today, 15:454-459, 2012.




J.S. Katz, K.A. Eisenbrown, E.D. Johnston, N.P. Kamat, J. Rawson, M.J. Therien, J.A. Burdick, D.A. Hammer, Soft Biodegradable Polymersomes from Caprolactone-Derived Polymers, Soft Matter, 8:10853-10862, 2012.




B.M. Baker, R.P. Shah, A.M. Silverstein, J.L. Esterhai, J.A. Burdick, R.L. Mauck, Sacrificial Nanofibrous Composites Provide Instruction without Impediment and Enable Functional Tissue Formation, Proceedings of the National Academy of Sciences (PNAS), 109:14176-14181, 2012.




S.W. Lee, K.E. Tettey, I.L. Kim, J.A. Burdick, D. Lee, Controlling the Cell-Adhesion Properties of Poly(acrylic acid)/Polyacrylamide Hydrogen-Bonded Multilayers, Macromolecules, 45:6120-6126, 2012.




B.P. Purcell, J.A. Elser, A. Mu, K.B. Margulies, J.A. Burdick, Synergistic Effects of SDF-1a Chemokine and Hyaluronic Acid Release from Degradable Hydrogels on Directing Bone Marrow Derived Cell Homing to Myocardium, Biomaterials, 33:7849-7857, 2012.




E. Tous, H.M. Weber, M.H. Lee, K.J. Koomalsingh, T. Shuto, N. Kondo, J.H. Gorman, D. Lee, R.C. Gorman, J.A. Burdick, Tunable Hydrogel-Microsphere Composites that Modulate Local Inflammation and Collagen Bulking, Acta Biomaterialia, 8:3218-3227, 2012.




R.A. Marklein, D.E. Soranno, J.A. Burdick, Magnitude and Presentation of Mechanical Signals Influence Adult Stem Cell Behavior in 3-Dimensional Macroporous Hydrogels, Soft Matter, 8:8113-8120, 2012.PDF




D. Hanjaya-Putra, K. Wong, K. Hirotsu, S. Khetan, J.A. Burdick, S. Gerecht, Spatial Control of Cell-Mediated Degradation to Regulate Vasculogenesis and Angiogenesis in Synthetic Hydrogels, Biomaterials, 33:6123-6131, 2012.




I.E. Erickson, S.R. Kestle, K.H. Zellars, M.J. Farrell, M. Kim, J.A. Burdick, R.L. Mauck, High Stem Cell Seeding Densities in Hyaluronic Acid Hydrogels Produce Engineered Cartilage with Native Tissue Properties, Acta Biomaterialia, 3027-3034, 2012.




M. Guvendiren and J.A. Burdick, Stiffening Hydrogels to Probe Short- and Long-Term Cellular Responses to Dynamic Mechanics, Nature Communications, 3:792, 2012. PDF




J.A. Burdick, Injectable Gels for Organ/Tissue Repair, Biomedical Materials, 7:024100, 2012.




I.E. Erickson, S.R. Kestle, K.H. Zellars, G.R. Dodge, J.A. Burdick, R.L. Mauck, Improved Cartilage Repair via In Vitro Pre-Maturation of MSC Seeded Hyaluronic Acid Hydrogels, Biomedical Materials, 7:024110, 2012.




L. Bian, D.Y. Zhai, E.C. Zhang, R.L. Mauck, and J.A. Burdick, Dynamic Compressive Loading Enhances Cartilage Matrix Synthesis and Distribution and Suppresses Hypertrophy in hMSC-Laden Hyaluronic Acid Hydrogels, Tissue Engineering A, 18:715-724, 2012. PDF




H.D. Lu, M.B. Charati, I.L. Kim, J.A. Burdick, Injectable Shear-Thinning Hydrogels Engineered with a Self-Assembling Dock-and-Lock Mechanism, Biomaterials, 33:2145-2133, 2012. PDF




J.A. Elser, B.P. Purcell, I.A. Allana, J.A. Burdick, K.B. Margulies, Ischemia Induces Selective Progenitor Cell Engraftment in the Isolated-Perfused Heart, Journal of Molecular and Cellular Cardiology, 52:105-112, 2012.




M.H. Lee, K.C. Hribar, T. Brugarolas, N.P. Kamat, J.A. Burdick, D. Lee, Harnessing Interfacial Phenomena to Program the Release Properties of Hollow Microspheres, Advanced Functional Materials, 22:131-138, 2012.




M. Guvendiren, H.D. Lu, and J.A. Burdick, Shear-Thinning Hydrogels for Biomedical Applications, Soft Matter, 8:260-272, 2012. PDF




M. Guvendiren, B. Purcell, J.A. Burdick, Photopolymerizable Systems, in Comprehensive Polymer Science (eds. R. Langer and D. Tirrell), Elsevier, 2012.

V.V. Ramanan, K.C. Hribar, J.S. Katz, J.A. Burdick, Nanofiber-Nanorod Composites Exhibiting Light-Induced Reversible LCST Transitions, Nanotechnology, 22:494009, 2011. PDF




E. Tous, J.L. Ifkovits, K.J. Koomalsingh, T. Shuto, T. Soeda, N. Kondo, J.H. Gorman, R.C. Gorman, J.A. Burdick, Influence of Injectable Hyaluronic Acid Hydrogel Degradation Behavior on Infarction Induced Ventricular Remodeling, Biomacromolecules, 12:4127-4135, 2011. PDF




J.A. Burdick and F.M. Watt, High-throughput Stem Cell Niches, Nature Methods, 8:915-916, 2011.




I.L. Kim, R.L. Mauck, J.A. Burdick, Hydrogel Design for Cartilage Tissue Engineering - A Case Study with Hyaluronic Acid, Biomaterials, 32:8771-8782, 2011. PDF




E. Tous, B.P. Purcell, J.L. Ifkovits, J.A. Burdick, Injectable Acellular Hydrogels for Cardiac Repair, Journal of Cardiovascular Translational Research, 4:528-542, 2011. PDF




M. Morita, C.E. Eckert, K. Matsuzaki, M. Noma, L.P. Ryan, J.A. Burdick, B.M. Jackson, J.H. Gorman, M.S. Sacks, R. C. Gorman, Modification of Infarct Material Properties Limits Adverse Ventricular Remodeling, Annals of Thoracic Surgery, 92:617-624, 2011.




D. Hanjaya-Pura, V. Bose, Y.I. Shen, J. Yee, S. Khetan, J.A. Burdick, S. Gerecht, Controlled Activation of Morphogenesis to Generate Functional Human Microvasculature in a Synthetic Matrix, Blood, 118:804-815, 2011.




L. Bian, D.Y. Zhai, E. Tous, R. Rai, R.L. Mauck, J.A. Burdick, Enhanced Chondrogenesis Following Delivery of TGF-b3 from Alginate Microspheres within Hyaluronic Acid Hydrogels In Vitro and In Vivo, Biomaterials, 12:2344-2350, 2011. PDF




H.G. Sundararaghavan and J.A. Burdick, Gradients with Depth in Electrospun Fibrous Scaffolds for Directed Cellular Behavior, Biomacromolecules, 12:2344-2350, 2011. PDF




K.C. Hribar, M.H. Lee, D. Lee, J.A. Burdick, Enhanced Release of Small Molecules from Near-Infrared Light Responsive Polymer-Nanorod Composites, ACS Nano, 5:2948-2956, 2011. PDF




J.A. Burdick and G. Prestwich, Hyaluronic Acid Hydrogels for Biomedical Applications, Advanced Materials, 23:H41-H56, 2011. PDF




L. Bian, D.Y. Zhai, R.L. Mauck, J.A. Burdick, Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage, Tissue Engineering A, 17-1137-1145, 2011. PDF




H. Sundararaghavan and J.A. Burdick, Cell Encapsulation, in Comprehensive Biomaterials (eds. P. Ducheyne, D. Hutmacher, J. Kirkpatrick, K. Healy), Elsevier, 2011.




R.C. Gorman, B.M. Jackson, J.A. Burdick and J.H. Gorman, Infarct Restraint to Limit Adverse Ventricular Remodeling, Journal of Cardiovascular Translational Research, 4:73-81, 2011.




S. Khetan and J.A. Burdick, Patterning Hydrogels in 3-Dimensions towards Controlling Cellular Interactions, Soft Matter, 7:830-838, 2011. PDF




J.A. Burdick and R.L. Mauck (editors), Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends, Springer Verlag, 2011.




D.M. Brey, N.A. Motlekar, J.P. Garino, S.L. Diamond, R.L. Mauck, J.A. Burdick, High-throughput Screening of a Small Molecule Library for Promoters and Inhibitors of Mesenchymal Stem Cell Osteogenic Differentiation, Biotechnology and Bioengineering, 108:163-174, 2011. PDF

J.L. Ifkovits, K. Wu, R.L. Mauck, J.A. Burdick, The Influence of Fibrous Elastomer Structure and Porosity on Matrix Organization, PLoS One, 5:e15717, 2010. PDF




M. Guvendiren, J.A. Burdick, S. Yang, Solvent Induced Transition from Wrinkles to Creases in Thin Film Gels with Depth-Wise Crosslinking Gradients, Soft Matter, 6:5795-5801, 2010.




V. Ramanan, J.S. Katz, M. Guvendiren, E. Cohen, R.A. Marklein, J.A. Burdick, Photocleavable Side Groups to Spatially alter Hydrogel Properties and Cellular Interactions, Journal of Materials Chemistry, 20:8920-8926, 2010. PDF




S. Khetan and J.A. Burdick, Patterning Network Structure to Spatially Control Cellular Remodeling and Stem Cell Fate within 3-Dimensional Hydrogels, Biomaterials, 31:8228-8234, 2010. PDF




M.B. Charati, I. Lee, K.C. Hribar, J.A. Burdick, Light-sensitive Polypeptide Hydrogel and Nanorod Composites, Small, 6:1608-1611, 2010. PDF




J.L. Ifkovits, E. Tous, M. Minakawa, M. Morita, J.D. Robb, K.J. Koomalsingh, J.H. Gorman, R.C. Gorman, J.A. Burdick, Injectable Hydrogel Properties Influence Extent of Post-Infarction Left Ventricular Remodeling in an Ovine Model, Proceedings of the National Academy of Sciences (PNAS), 107:11507-11512, 2010. PDF




M. Guvendiren and J.A. Burdick, The Control of Stem Cell Morphology and Differentiation by Hydrogel Surface Wrinkles, Biomaterials, 31:6511-6518, 2010. PDF




D.M. Brey, C. Chung, K.D. Hankenson, J.P. Garino, J.A. Burdick, Identification of Osteoconductive and Biodegradable Polymers from a Combinatorial Polymer Library, Journal of Biomedical Materials Research A, 93A:807-816, 2010. PDF




J.S. Katz and J.A. Burdick, Light-Responsive Biomaterials: Development and Applications, Macromolecular Bioscience, 10:339-348, 2010. PDF




M. Guvendiren, J.A. Burdick, S. Yang, Kinetic Study of Swelling-Induced Surface Pattern Formation and Ordering in Hydrogel Films with Depth-wise Crosslinking Gradients, Soft Matter, 6:2044-2049, 2010.




J.S. Katz, S. Zhong, B.G. Ricart, D.J. Pochan, D.A. Hammer, J.A. Burdick, Modular Synthesis of Biodegradable Diblock Copolymers for Designing Functional Polymersomes, Journal of the American Chemical Society (JACS), 132:3654-3655, 2010. PDF




L.C. Ionescu, G.C. Lee, B.J. Sennett, J.A. Burdick, R.L. Mauck, An Anisotropic Nanofiber/Microsphere Composite with Controlled Release of Biomolecules for Fibrous Tissue Engineering, Biomaterials, 31:4113-4120, 2010.




H.G. Sundararaghavan, R.B. Metter, J.A. Burdick, Electrospun Fibrous Scaffolds with Multi-scale and Photopatterned Porosity, Macromolecular Bioscience, 10:265-270, 2010. PDF




R.B. Metter, J.L. Ifkovits, K. Hou, L. Vincent, B. Hsu, L. Wang, R.L. Mauck, J.A. Burdick, Biodegradable Fibrous Scaffolds with Diverse Properties by Electrospinning Candidates from a Combinatorial Macromer Library, Acta Biomaterialia, 6:1219-1226, 2010. PDF




S. Khetan, V. Ramanan, and J.A. Burdick, 3D Encapsulation of Cells in Hydrogels using Radical and Addition Polymerizations, in 3-D Tissue Engineering (Methods in Bioengineering) (eds. M.L. Yarmush and R.S. Langer), Artech House Publishing, 2010.




R.L. Mauck and J.A. Burdick, Engineering Cartilage Tissue, in The Tissue Engineering Book: State of the Art, Visions, and Limitations (ed. N. Pallua), Springer Science + Business Media, 2010.




R.A. Marklein and J.A. Burdick, Controlling Stem Cell Fate with Material Design, Advanced Materials, 22:175-189, 2010. PDF




R.A. Marklein and J.A. Burdick, Spatially Controlled Hydrogel Mechanics to Modulate Stem Cell Interactions, Soft Matter, 6:136-143, 2010. PDF

S. Khetan and J.A. Burdick, Cellular Encapsulation in 3D Hydrogels for Tissue Engineering, Journal of Visualized Experiments, 32, 2009. PDF




J.L. Ifkovits, H.G. Sundararaghavan, and J.A. Burdick, Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture, Journal of Visualized Experiments, 32, 2009. PDF




I.E. Erickson, A.H. Huang, S. Sengupta, S. Kestle, J.A. Burdick, R.L. Mauck, Macromer Density Influences Mesenchymal Stem Cell Chondrogenesis and Maturation in Photocrosslinked Hyaluronic Acid Hydrogels, Osteoarthritis and Cartilage, 17:1639-1648, 2009.




M. Guvendiren, S. Yang, J.A. Burdick, Swelling-induced Surface Patterns in Hydrogels with Gradient Crosslinking Density, Advanced Functional Materials,19:3038-3045, 2009. PDF




J.L. Ifkovits, J.J. Devlin, G. Eng, T.P. Martens, G. Vunjak-Novakovic, J.A. Burdick, Photocrosslinked Biodegradable Fibrous Scaffolds with Tunable Properties for Tissue Engineering Applications, Applied Materials and Interfaces, 1:1878-1886, 2009. PDF




P.M. George, R. Saigal, M. Lawlor, M.J. Moore, D.A. LaVan, R. Marini, M. Selig, M. Makhni, J.A. Burdick, R. Langer, D.S. Kohane, Stand-Alone Three-Dimensional Conductive Constructs for Nerve Regeneration and Other Applications, Journal of Biomedical Materials Research A, 91A:519-527, 2009.




B.M. Baker, N.L. Nerurkar, J.A. Burdick, D.M. Elliott, R.L. Mauck, Fabrication and Modeling of Dynamic Multi-Polymer Nanofibrous Scaffolds, Journal of Biomechanical Engineering, 131:101012, 2009.




M.B. Charati, J.L. Ifkovits, J.A. Burdick, J.G. Linhardt, K.L. Kiick, Hydrophilic Elastomeric Biomaterials based on Resilin-like Polypeptides, Soft Matter, 5:3412-3416, 2009.




A. Peters, D.M. Brey, J.A. Burdick, High-throughput and Combinatorial Technologies for Tissue Engineering Applications, Tissue Engineering B, 15:225-239, 2009. PDF




K.C. Hribar, R.B. Metter, J.L. Ifkovits, T. Troxler, J.A. Burdick, Light-Induced Temperature Transitions in Biodegradable Polymer and Nanorod Composites, Small, 5:1830-1834, 2009. PDF




R.L. Mauck, B.M. Baker, N.L. Neururkar, J.A. Burdick, W.J. Li, R.S. Tuan, D.M. Elliott, Engineering on the Straight and Narrow: The Mechanics of Nanofibrous Assemblies for Fiber-Reinforced Tissue Regeneration, Tissue Engineering B, 15:171-193, 2009.




C. Chung, M. Beecham, R.L. Mauck, J.A. Burdick, Tailored Hydrogel Crosslinking and Degradation to Enhance Neocartilage Formation by Mesenchymal Stem Cells in Hyaluronic Acid Hydrogels, Biomaterials, 30:4287-4296, 2009. PDF




M. Brigham, A. Bick, E. Lo, A. Bendali, J.A. Burdick, A. Khademhosseini, Mechanically Robust and Bioadhesive Collagen and Photocrosslinkable Hyaluronic Acid Semi-Interpenetrating Networks, Tissue Engineering A, 15:1633-643, 2009.




J.A. Burdick, Cellular Control in Two Clicks, Nature, 260:469-470, 2009. PDF




I.E. Erickson, A.H. Huang, C. Chung, R. Li, J.A. Burdick, R.L. Mauck, Differential Maturation and Structure-Function Relationships in Mesenchymal Stem Cell and Chondrocyte Seeded Hydrogels, Tissue Engineering A, 15:1041-1052, 2009.




J.S. Katz, D.H. Levine, K.P. Davis, F.S. Bates, D.A. Hammer, J.A. Burdick, Membrane Stabilization of Biodegradable Polymersomes, Langmuir, 25:4429-4434, 2009. PDF




S. Khetan, J.S. Katz, J.A. Burdick, Sequential Crosslinking to Control Cellular Spreading in 3-Dimensional Hydrogels, Soft Matter, 5:1601-1606, 2009. PDF




J.A. Burdick and G. Vunjak-Novakovic, Engineering the Cellular Microenvironment for Controlled Stem Cell Differentiation, Tissue Engineering A, 15:205-219, 2009. PDF




C. Chung and J.A. Burdick, Influence of 3D Hyaluronic Acid Microenvironments on Mesenchymal Stem Cell Chondrogenesis, Tissue Engineering A, 15:243-254, 2009. PDF




J.S. Katz and J.A. Burdick, Hydrogel Mediated Delivery of Trophic Factors for Neural Repair, Wiley Interdisciplinary Reviews – Nanomedicine, 1:128-139, 2009. PDF




R.D. Hubbard, J.J. Martinez, J.A. Burdick, B.A. Winkelstein, Controlled Release of GDNF Reduces Nerve Root-Mediated Behavioral Hypersensitivity, Journal of Orthopaedic Research, 27:120-127, 2009.

A.R. Tan, B.M. Baker, J.L. Ifkovits, D.M. Brey, R.L.Mauck, J.A. Burdick, Electrospinning of Photocrosslinked and Degradable Fibrous Scaffolds, Journal of Biomedical Materials Research A, 87A:1034-1043, 2008. PDF




J.L. Ifkovits, R.F. Padera, and J.A. Burdick, Biodegradable and Radically Polymerized Elastomers with Enhanced Processing Capabilities, Biomedical Materials, 3:034104, 2008. PDF




C. Chung, I.E. Erickson, R.L. Mauck, J.A. Burdick, Differential Behavior of Auricular and Articular Chondrocytes in Hyaluronic Acid Hydrogels, Tissue Engineering, 14:1121-1131, 2008. PDF




S. Sahoo, C. Chung, S. Khetan, J.A. Burdick, Hydrolytically Degradable Hyaluronic Acid Hydrogels with Controlled Temporal Network Structures, Biomacromolecules, 9:1088-1092, 2008. PDF




D.M. Brey, I. Erickson, and J.A. Burdick, Influence of Macromer Molecular Weight and Chemistry on Poly(b-amino ester) Network Properties and Initial Cell Interactions, Journal of Biomedical Materials Research A, 85A:731-741, 2008. PDF




B.M. Baker, A.O. Gee, R.B. Metter, A.S. Nathan, R.L. Marklein, J.A. Burdick, R.L. Mauck, The Potential to Improve Cell Infiltration by the Selective Removal of Sacrificial Fibers, Biomaterials, 29:2348-2358, 2008.




D.M. Brey, J.L. Ifkovits, R. Mozia, J.S. Katz, and J.A. Burdick, Controlling Poly(b-amino ester) Network Properties through Macromer Branching, Acta Biomaterialia, 4:207-217, 2008. PDF




C. Chung and J.A. Burdick, Engineering Cartilage Tissue, Advanced Drug Delivery Reviews, 60:243-262, 2008. PDF

J.L. Ifkovits and J.A. Burdick, Photopolymerizable and Degradable Biomaterials for Tissue Engineering Applications, Tissue Engineering, 13:2369-2385, 2007. PDF




S. Gerecht, J.A. Burdick, L.S. Ferreira, S.A. Townsend, R. Langer, G. Vunjak-Novakovic, Hyaluronic Acid Hydrogel for Controlled Self-renewal and Differentiation of Human Embryonic Stem Cells, Proceedings of the National Academy of Sciences (PNAS), 104:11298-11303, 2007.




E. Figallo, C. Cannizzaro, S. Gerecht, J.A. Burdick, R. Langer, N. Elvassore, G. Vunjak-Novakovic, Micro Bioreactor Array for Controlling Cellular Microenvironments, Lab on a Chip, 7:710-719, 2007.




S. Gerecht, J.A. Burdick, C. Cannizzaro, G. Vunjak-Novakovic, 3D Cultivation of Human Embryonic Stem Cells, in Human Embryonic Stem Cells (eds. J. Masters, B. Palsson, J. Thomson), Springer Verlag, 2007.




Y. Yeo, W. Geng, T. Ito, D.S. Kohane, J.A. Burdick, M. Radisic, Photocrosslinkable Hydrogel for Myocyte Cell Culture and Injection, Journal of Biomedical Materials Research B, Applied Biomaterials, 81B:312-322, 2007.

A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling, R. Langer, J.A. Burdick, Micromolding of Photocrosslinkable Hyaluronic Acid for Cell Encapsulation and Entrapment, Journal of Biomedical Materials Research A, 79A:522-532, 2006.




D.G. Anderson, C.A. Tweedie, N. Hossain, S.M. Navarro, D.M. Brey, K.J. Van Vliet, R. Langer, J.A. Burdick, A Combinatorial Library of Photocrosslinkable and Degradable Materials, Advanced Materials, 18:2614-2618, 2006.




J. Piantino, J.A. Burdick, D. Goldberg, R. Langer, L.I. Benowitz, An Injectable, Degradable Hydrogel for Trophic Factor Delivery Enhances Axonal Rewiring and Improves Performance after Spinal Cord Injury, Experimental Neurology, 201: 359-367, 2006.




C. Chung, J. Mesa, G.J. Miller, M.A. Randolph, T. Gill, J.A. Burdick, Effects of Auricular Chondrocyte Expansion on Neocartilage Formation in Photocrosslinkable Hyaluronic Acid Networks, Tissue Engineering, 12:2665-2673, 2006. PDF




C. Chung, J. Mesa, M.A. Randolph, M. Yaremchuk, J.A. Burdick, Influence of Gel Properties on Neocartilage Formation by Auricular Chondrocytes Photoencapsulated in Hyaluronic Acid Networks, Journal of Biomedical Materials Research A, 77A: 518-525, 2006. PDF




Y. Yeo, J.A. Burdick, C.B. Highley, R. Marini, R. Langer, D.S. Kohane, Peritoneal Application of Chitosan and UV-crosslinkable Chitosan, Journal of Biomedical Materials Research A, 78A: 668-675, 2006.




P.M. George, D.A. LaVan, J.A. Burdick, C.Y. Chen, E. Liang, R. Langer, Electrically Controlled Drug Delivery from a Biotin-Doped Conductive Polypyrrole, Advanced Materials, 18: 577-581, 2006.




J.A. Burdick, M. Ward, E. Liang, M.J. Young, R. Langer, Stimulation of Neurite Outgrowth by Neurotrophins Delivered from Degradable Hydrogels, Biomaterials, 27: 452-459, 2006.

J.A. Burdick and Molly M. Stevens, Biomedical Hydrogels, in Biomaterials, Artificial Organs, and Tissue Engineering (eds. J. Jones and L. Hench), Woodhead Publishing Ltd., Cambridge, 2005.




B.A. Pfeifer, J.A. Burdick, S. Little, R. Langer, Poly(ester-anhydride):Poly(b-amino ester) Micro- and Nanospheres: DNA Encapsulation and Cellular Transfection, International Journal of Pharmaceutics, 304, 210-219, 2005.




S. Levenberg, J.A. Burdick, T. Kraehenbuehl, R. Langer, Neurotrophin Induced Differentiation of Human Embryonic Stem Cells on 3-Dimensional Polymeric Scaffolds, Tissue Engineering, 11: 506-512, 2005.




J.A. Burdick, C. Chung, X. Jia, M.A. Randolph, R. Langer, Controlled Degradation and Mechanical Behavior of Photopolymerized Hyaluronic Acid Networks, Biomacromolecules, 6: 386-391, 2005.




B.A. Pfeifer, J.A. Burdick, R. Langer, Formulation and Surface Modification of Poly(Ester-Anhydride) Micro- and Nanospheres, Biomaterials, 26: 117-124, 2005.




T.M. Lovestead, J.A. Burdick, K.S. Anseth, C.N. Bowman, Understanding Multivinyl Monomer Photopolymerization Kinetics through Modeling and GPC Investigation of Degradable Networks, Polymer, 46: 6226-6234, 2005.




D.G. Anderson, J.A. Burdick, R. Langer, Smart Biomaterials, Science, 305: 1923-1924, 2004.




A. Khademhosseini, J. Yeh, S. Jon, G. Eng, K.Y. Suh, J.A. Burdick, R. Langer, Molded PEG Microstructures for Capturing and Shear Protecting Cells Within Microfluidic Channels, Lab On A Chip, 4: 425-430, 2004.




J.A. Burdick, A. Khademhosseini, R. Langer, Fabrication of Gradient Hydrogels Using a Microfluidics/ Photopolymerization Process, Langmuir, 20: 5153-5156, 2004.




X. Jia, J.A. Burdick, J. Kobler, R.J. Clifton, J.J. Rosowski, S.M. Zeitels, R. Langer, Synthesis and Characterization of In Situ Crosslinkable Hyaluronic Acid-Based Hydrogels with Potential Application for Vocal Fold Regeneration, Macromolecules, 37: 3239-3248, 2004.




J.A. Burdick, T. Lovestead, K.S. Anseth, Kinetic Chain Lengths in Highly Crosslinked Networks Formed by the Photoinitiated Polymerization of Degradable Divinyl Monomers: A GPC Investigation, Biomacromolecules, 4: 149-156, 2003.




K.A. Davis, J.A. Burdick, K.S. Anseth, Photopolymerized Crosslinked Degradable Copolymer Networks for Tissue Engineering Applications, Biomaterials, 24: 2485-2495, 2003.




J.A. Burdick, W.S. Dernell, D. Frankel, K.S. Anseth, An Initial Investigation of Photocurable 3-Dimensional Lactic Acid Based Scaffolds in a Critical-Sized Cranial Defect, Biomaterials, 24: 1613-1620, 2003.




A.K. Poshusta, J.A. Burdick, D.J. Mortisen, R.F. Padera, D. Ruehlman, M.J. Yaszemski, K.S. Anseth, Histocompatibility of Photocrosslinked Polyanhydrides: A Novel In Situ Forming Orthopaedic Biomaterial, Journal of Biomedical Materials Research, 64A: 62-69, 2003.




J.A. Burdick, M.N. Mason, A.D. Hinman, K. Thorne, K.S. Anseth, Delivery of Osteoinductive Growth Factors from Degradable PEG Hydrogels Influences Osteoblast Differentiation and Mineralization, Journal of Controlled Release, 83: 53-63, 2002.




J.A. Burdick and K.S. Anseth, Photoencapsulation of Osteoblasts in Injectable RGD-Modified PEG Hydrogels for Bone Tissue Engineering, Biomaterials, 23: 4315-4323, 2002.




J.A. Burdick, R.F. Padera, J.V. Huang, K.S. Anseth, An Investigation of the Cytotoxicity and Histocompatibility of In Situ Forming Lactic Acid Based Orthopaedic Biomaterials, Journal of Biomedical Materials Research (Applied Biomaterials), 63: 484-491, 2002.




K.S. Anseth and J.A. Burdick, New Directions in Photopolymerizable Biomaterials, MRS Bulletin, 27:130-138, 2002.




J.A. Burdick, M.N. Mason, K.S. Anseth, In Situ Forming Lactic Acid Based Orthopaedic Biomaterials: Influence of Oligomer Chemistry on Osteoblast Attachment and Function, Journal of Biomaterials Science, Polymer Edition 12: 1253-1265, 2001.




J.A. Burdick, L.M. Philpott, K.S. Anseth, Synthesis and Characterization of Tetrafunctional Lactic Acid Oligomers: A Potential In Situ Forming Orthopaedic Biomaterial, Journal of Polymer Science, A, Polymer Chemistry 39: 683-692, 2001.




J.A. Burdick, A.J. Peterson, K.S. Anseth, Conversion and Temperature Profiles During the Photoinitiated Polymerization of Thick Orthopaedic Biomaterials, Biomaterials 22: 1779-1786, 2001.




A.K. Burkoth, J. Burdick, K.S. Anseth, Surface and Bulk Modifications to Photocrosslinked Polyanhydrides to Control Degradation Behavior, Journal of Biomedical Materials Research 51: 352-359, 2000.

Department of Bioengineering
School of Engineering and Applied Science
University of Pennsylvania
210 S. 33rd Street 
Room 240 Skirkanich Hall 
Philadelphia, PA 19104

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