Honors and Awards: Alfred P. Sloan Foundation Research Faculty Fellow - 2009, David and Lucile Packard Fellow - 2009, Burroughs Wellcome Fund Career Award - 2005
Joshua uses mathematics and computation to study questions in evolutionary biology and ecology. His research group is primarily concerned with the origin and maintenance of genetic variation within populations. A central focus is the development of statistical methods for inferring the action of natural selection from intra-specific polymorphism data and from inter-specific sequence variation. Joshua is also engaged in studying the evolution of robustness and adaptability, the evolutionary ecology of viral populations, somatic evolution, stochastic population dynamics, and the evolution of social norms.
PhD Applied Mathematics 2003 - Princeton University
- Selection for protein stability enriches for epistatic interactions, Posfai, A. | Zhou, J. | McCandlish, D.M. | Plotkin, J.B. | Kinney, J.B., Genes, 2018
- Codon usage influences fitness through RNA toxicity, Mittal, P. | Brindle, J. | Stephen, J. | Plotkin, J.B. | Kudla, G., Proceedings of the National Academy of Sciences of the United States of America, 2018
- Inferring the shape of global epistasis, Otwinowski, J. | McCandlish, D.M. | Plotkin, J.B., Proceedings of the National Academy of Sciences of the United States of America, 2018
- Phenotypic plasticity promotes recombination and gene clustering in periodic environments, Gulisija, D. | Plotkin, J.B., Nature communications, 2017
- The evolutionary advantage of heritable phenotypic heterogeneity /631/181/2474 /631/181/2468 article, Carja, O. | Plotkin, J.B., Scientific Reports, 2017