Principle Investigator

David F. Meaney, Ph.D.

Solomon R. Pollack Professor and Chair of Bioengineering

 

BSE in Biomedical Engineering, Rensselaer Polytechnic Institute, 1987
MSE, 1989 and Ph.D., 1991, in Bioengineering, The University of Pennsylvania

Interests

  • Understanding mechanical cues that regulate CNS injury and repair
  • Multiscale integration of mechanical injury response from synaptic spines to neural networks
  • Mechanisms of network dysfunction and therapeutic targets for repair

 

 

 

Post-Doctoral Fellows

Anthony Choo, Ph.D.Publications

BASc in Engineering Science, University of Toronto, 1998
MASc in Mechanical Engineering, University of British Columbia, 2001
PhD in Mechanical Engineering, University of British Columbia, 2007

Interests
  • Traumatic brain and spinal cord injury
  • Neuroengineering and neurophotonics
  • Neuronal Networks and Oscillations
  • In vivo multiphoton imaging
  • Computational Modeling and image analysis

Rosalind E. Mott, Ph.D.Publications

BS in Biomedical Engineering, Johns Hopkins University, 1999
Ph.D. Biomedical Engineering, University of Virginia, 2008

Interests
  • Cell adhesions, cytoskeleton and their role in mechanotransduction.
  • Mechanisms of local mRNA translation.
  • The impact of injuryd on mRNA translation and synaptic plasticity.
  • The interplay between network activity and synaptic plasticity.

Ph.D. Candidates

Yung Chia ChenPublications

BSE in Mechanical Engineering, University of Maryland, Baltimore County
Ph.D. Candidate

Interests
  • Changes in astrocytic signaling after neuronal trauma
  • In vivo 2-photon imaging
  • Mechanical injury to hippocampal slice cultures
  • Dissociated cell culture injury

Tapan PatelPublications

BS Biochemistry, Mathematics, University of Delaware, 2007
M.D./Ph.D. Candidate, University of Pennsylvania

Interests
  • Functional Multineuronal Calcium Imaging
  • Neural network topology following in vitro or in vivo injury
  • Multiscale computational model of neural network activity
  • Automated analysis of neurobehavior

 

Research Specialists

Tanya Merdiushev

BS, Biology, Conneticut University
Executive Master's in Technology Management, Univeristy of Pennsylvania

Interests
  • Lab management

David Gullotti

BS in Physics and Biology, Loyola University Maryland, 2010

Interests
  • Computational modeling
  • Effects of blast injury on neurobehavior

Patricia Slobodnik

MS, Biotechnology (Thomas Jefferson University)

Interests
  • Cell culture
  • Controlled cortical impact

Matt Beamer

BS in Biology

Interests
  • Neurobehavior
  • Mouse breeding, genotyping

Undergraduate assistants

  • Linda Le (Chemical Engineering, 2012)
  • Daphne Lew (Bioengineering, 2012)
  • Scott Ventre (Bioengineering, 2013)
  • Tom Woltemate (Biology, 2014)

Lab Alumni

  • Jenn Singh, Ph.D., Post-Doctoral fellow at University of Pennsylvania
  • Catherine von Reyn, Ph.D., Post-Doctoral fellow at Janelia Farms HHMI
  • Pallab Singh, Ph.D., Patent Law firm
  • Mahlet Mesfin, Ph.D., National Academy of Sciences
  • Vineet Tiruvadi, B.S./M.S., Emory/Georgia Tech (MD/PhD candidate)
  • Adam Hockenberry, B.A., Northwestern University (Ph.D. candidate)
  • Bill Miller, Ph.D., Swiftwater Group consulting
  • Dave Shreiber, Ph.D., Rutgers University (Associate Professor of Biomedical Engineering)
  • Donna Geddes-Klein, Ph.D., Research Scientist, Centyrex Venture at Centocor
  • Mike DeRidder, Ph.D.,
  • Phil Nibley, B.S., Drexel Medical School
  • Emory Kuo, B.S.E., Philadelphia College of Osteopathic Medicine
  • Kelly McManus, B.S.,
  • Brittainy Wierzbicki, B.S., Temple University (Occupational Therapy)
  • Dave Scarsella, B.S.