Andrew Dolan

Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Tel: 215-746-4571
Email: adolan@seas.upenn.edu

Education

M.S., Chemical and Biomolecular Engineering, University of Pennsylvania, 2010
B.S., Chemical Engineering, Johns Hopkins University, 2008

Research Projects

Computational modeling of platelet calcium signaling

Research Summary
I am working on modeling how platelets respond to external stimuli. Using Monte Carlo sampling techniques we are able to characterize how different resting configurations affect the platelet's subsequent response to an activating signal. In particular we have developed a working model for the process of store-operated calcium entry which functions with parameters and displays dynamic behavior that is consistent with observations reported in scientific literature.